Results 21 to 30 of about 299,300 (300)
Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa [PDF]
, 2016 The Fc region of Immunoglobulin G (IgG) initiates inflammatory responses such as antibody-dependent cell-mediated cytotoxicity (ADCC) through binding to activating Fc receptors (FcγRI, FcγRIIa, FcγRIIIa).
Ahmed, Alysia A. +3 more
core +2 more sources
Pentraxins and Fc Receptor-Mediated Immune Responses
Frontiers in Immunology, 2018 C-reactive protein (CRP) is a member of the pentraxin family of proteins. These proteins are highly conserved over the course of evolution being present as far back as 250 million years ago.
Jinghua Lu +4 more
doaj +1 more source
PLoS ONE, 2020 Cytokine signaling is transmitted by cell surface receptors which act as natural biological switches to control cellular functions such as immune reactions.
Sofie Mossner +5 more
doaj +1 more source
pH Dependence and Stoichiometry of Binding to the Fc Region of IgG by the Herpes Simplex Virus Fc Receptor gE-gI [PDF]
, 2004 Herpes simplex virus type 1 encodes two glycoproteins, gE and gI, that form a heterodimer on the surface of virions and infected cells. The gE-gI heterodimer has been implicated in cell-to-cell spread of virus and is a receptor for the Fc fragment of IgG.
Bjorkman, Pamela J. +2 more
core +1 more source
Annual Review of Immunology, 2003 The IgA receptor family comprises a number of surface receptors including the polymeric Ig receptor involved in epithelial transport of IgA/IgM, the myeloid specific IgA Fc receptor (FcαRI or CD89), the Fcα/μR, and at least two alternative IgA receptors.
Monteiro, R.C., van de Winkel, J.G.J.
openaire +3 more sources
, 2008 The aggregation of cell surface Fc receptors by immune complexes induces a number of important antibody-dependent effector functions. It is becoming increasingly evident that the organization of key immune proteins has a significant impact on the function of these proteins.
Maree S, Powell, P Mark, Hogarth
+6 more sources
Inside-Out Control of Fc-Receptors
Frontiers in Immunology, 2019 Receptors recognizing the Fc-part of immunoglobulins (FcR) are important in the engagement of phagocytes with opsonized micro-organisms, but they also play a major role in the pathogenesis of chronic inflammatory diseases. Different FcRs are specifically
Leo Koenderman
doaj +1 more source
Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]
, 1999 Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J. +5 more
core +1 more source
Journal of Acute Disease, 2019 Objective: To explore the possible IgG1 binding receptors by protein-protein docking experiments. Methods: The protein-protein cognate interactions such as IgG with Fc Receptors (FcRs) potentiate signaling cascades to ameliorate antigen uptake ...
Shweta Saxena +3 more
doaj +1 more source
Enhanced metabolism of LDL aggregates mediated by specific human monocyte IgG Fc receptors.
Journal of Lipid Research, 1995 Macrophage-derived foam cells are important constituents of atheromatous lesions. In addition to the scavenger receptor pathway, uptake of immune complexed lipoproteins through IgG Fc receptors (Fc gamma receptors) represents an additional pathway of ...
P M Morganelli +3 more
doaj +1 more source