Results 201 to 210 of about 149,331 (265)

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

GPCRs as key regulators in wound healing. [PDF]

Front Cell Dev Biol
Chen H, Zheng K, Xiao Y, Feng X, Zhang C, Zhang T, Luo F, Chuan H, Zheng H, Deng C, Li W.   +10 more
europepmc   +1 more source

Beyond attenuation: a translational review of curative-intent pharmacological targets in idiopathic pulmonary fibrosis. [PDF]

Front Med (Lausanne)
Mansour GK, Hajjar AW, Sukkarieh HH.
europepmc   +1 more source

Emerging agents that target signaling pathways in cancer fibroblast cells (Review). [PDF]

Int J Oncol
Wan Y, Liu XQ, Liu D, Li KD, Zhang DD.
europepmc   +1 more source

Fibroblasts as Immunological Sentinels in Cutaneous Inflammation: A Review. [PDF]

J Clin Med
Quan T.
europepmc   +1 more source

Advances in targeting myocardial fibrosis: integrating mechanisms and therapeutics. [PDF]

Front Cardiovasc Med
Xu Z, Zhao Y.
europepmc   +1 more source

Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail-Implications for Disease and Regeneration. [PDF]

Int J Mol Sci
Pulawska-Czub A, Jakhar A, Łukaszyk K, Kobielak K.   +3 more
europepmc   +1 more source