Results 251 to 260 of about 256,322 (306)

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Unravelling the pathophysiology of diabetic foot ulcer: insights into a complex wound healing process. [PDF]

Front Clin Diabetes Healthc
AbuHaweeleh MN, Ali S, Elsalakawi Y, Al-Khulaifi A, Maggio V, Rizzo M, Boudaka A.   +6 more
europepmc   +1 more source

Immunobiology of pulmonary fibrosis. [PDF]

Front Immunol
Bindu S, Yasmin H, Barman U, Pandit S, Masmoudi K, Kishore U.   +5 more
europepmc   +1 more source

Hyaluronan-Based Hybrid Systems as Growth Factor Carriers in the Treatment of Chronic Wounds. [PDF]

Int J Mol Sci
Ostróżka-Cieślik A, Tanwar A, Michalak M.   +2 more
europepmc   +1 more source

Genetic background of infantile hypophosphatemia: a narrative review. [PDF]

Transl Pediatr
Zeng X, Hu L.
europepmc   +1 more source

Angiogenesis Suppression via VEGF-VEGFR2 Inhibition and Stromal-Endothelial Crosstalk Disruption by Myrosinase-Activated Broccoli Extract. [PDF]

Molecules
Naletova I, La Mantia A, Malfa GA, Bianchi S, Arena D, Di Domenico V, Attanasio F, Di Giacomo C, Tomasello B.   +8 more
europepmc   +1 more source

The Matrisome as an Immunomodulator: A Role Far Beyond Its Structural Support. [PDF]

Biomolecules
Quan T.
europepmc   +1 more source

Fibroblast growth factor receptors and skeletogenesis

openaire   +1 more source