Results 101 to 110 of about 18,956 (224)
Experimental Physiology, Volume 111, Issue 4, Page 1733-1745, 1 April 2026.Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh +6 more
wiley +1 more source
Novel structural determinants of the human neutrophil chemotactic activity of leukotriene B. [PDF]
, 1981 A specific 5(S),12(R)-dihydroxy-eicosa-6,8,10(trans/trans/cis), 14(cis)-tetraenoic acid, designated leukotriene B, is generated by the lipoxygenation and subsequent enzymatic hydration of arachidonic acid in a variety of leukocytes. Leukotriene B elicits
Goetzl, EJ, Pickett, WC
core
Molecular Organization of Vomeronasal Chemoreception [PDF]
, 2011 The vomeronasal organ (VNO) has a key role in mediating the social and defensive responses of many terrestrial vertebrates to species- and sex-specific chemosignals.
Dulac, Catherine +6 more
core +2 more sources
British Journal of PharmacologyBackground and PurposeThe pattern recognition receptors, formyl peptide receptors, FPR1 and FPR2, are G protein‐coupled receptors that recognize many different pathogen‐ and host‐derived ligands. While FPR1 conveys pro‐inflammatory signals, FPR2 is linked with pro‐resolving outcomes.
Denise Pajonczyk +5 more
openaire +2 more sources
Technology in Cancer Research & Treatment, 2020 Chronic inflammation is a causative factor of many cancers, although it originally acts as a protective host response to the loss of tissue homeostasis. Many inflammatory conditions predispose susceptible cells, most of which are of epithelial origin, to
Cuimeng Tian MD +5 more
doaj +1 more source
Intranuclear Signaling Cascades Triggered by Nuclear GPCRs
, 2016 G protein-couped receptors (GPCRs) play a key role on cellular membranes, where they respond to a broad array of extracellular signals such as lipids, peptides, proteins and sensory agents.
AMMENDOLA, ROSARIO +4 more
core +1 more source
Formyl-methionine as a degradation signal at the N-termini of bacterial proteins [PDF]
, 2015 In bacteria, all nascent proteins bear the pretranslationally formed N-terminal formyl-methionine (fMet) residue. The fMet residue is cotranslationally deformylated by a ribosome-associated deformylase.
Hwang, Cheol-Sang +3 more
core +3 more sources
Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models [PDF]
, 2016 Background: Harnessing the actions of the resolvin pathways has the potential for the treatment of a wide range of conditions associated with overt inflammatory signalling.
Bennett, Andrew +4 more
core +5 more sources
Cardioprotective Actions of the Annexin-A1 N-Terminal Peptide, Ac2-26, Against Myocardial Infarction
Frontiers in Pharmacology, 2019 The anti-inflammatory, pro-resolving annexin-A1 protein acts as an endogenous brake against exaggerated cardiac necrosis, inflammation, and fibrosis following myocardial infarction (MI) in vivo.
Cheng Xue Qin +23 more
doaj +1 more source
Effect of SXWS/WSXWS peptides on chemotaxis and adhesion of the macrophage-like cell line J774 [PDF]
, 2015 WSXWS motif is a conserved amino acid sequence that is present in type I cytokine receptors. This motif that can be found both in the ligand binding chains and signal transducer molecule of the receptors with different amino acids at the position “X ...
Bazan +22 more
core +1 more source