Extra-Gonadal and Non-Canonical Effects of FSH in Males
Recombinant follicle-stimulating hormone (FSH) is commonly used for the treatment of female infertility and is increasingly being used in males as well, as recommended by notable guidelines.
Matteo Spaziani +12 more
doaj +1 more source
Functional Divergence of Glycoprotein Hormone Receptors [PDF]
Two lamprey glycroprotein hormone receptors (lGpH-R I and II) highly similar with gnathostome GpH-Rs were cloned from sea lamprey testes and thyroid, respectively.
Freamat, Mihael, Sower, Stacia A.
core +3 more sources
Functional Expression of FSH Receptor in Endometriotic Lesions [PDF]
FSH receptor (FSHR), besides being expressed in gonads, is also expressed in some extragonadal tissues at low levels.We examined the functional expression of FSHR in different types of endometriotic lesions.Extensive studies were carried out to detect functional FSHR expression and FSH-stimulated estrogen production in ovarian endometriomas and recto ...
Ponikwicka-Tyszko D +11 more
openaire +3 more sources
The traditional view of follicle-stimulating hormone (FSH) as a reproductive hormone is changing. It has been shown that FSH receptors (FSHRs) are expressed in various extra-gonadal tissues and mediate the biological effects of FSH at those sites ...
Daria Lizneva +11 more
doaj +1 more source
Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
A. Monteiro +63 more
core +2 more sources
Generating FSH antagonists and agonists through immunization against FSH receptor N-terminal decapeptides [PDF]
Follicle-stimulating hormone (FSH) via interaction with G-protein coupled specific receptors plays a central role in the control of gametogenesis in mammals of both sexes. In females, FSH is crucial for follicle growth, follicle maturation and ovulation.
Abdennebi, Latifa +5 more
openaire +4 more sources
Fsh controls gene expression in fish both independently of and through steroid mediation. [PDF]
The mechanisms and the mediators relaying Fsh action on testicular functions are poorly understood. Unlike in mammals, in fish both gonadotropins (Fsh and Lh) are able to efficiently stimulate steroidogenesis, likely through a direct interaction with ...
Elisabeth Sambroni +2 more
doaj +1 more source
Duplicated membrane estrogen receptors in the European sea bass (Dicentrarchus labrax): Phylogeny, expression and regulation throughout the reproductive cycle [PDF]
The numerous estrogen functions reported across vertebrates have been classically explained by their binding to specific transcription factors, the nuclear estrogen receptors (ERs).
Alvarado, M. Victoria +5 more
core +1 more source
FSH Receptor and FSH Beta Chain Polymorphism Involvement in Infertility and Endometriosis Disease
The purpose of this study was to evaluate the association between the follicle-stimulating hormone (FSH) receptor (c.-29G>A) and FSH beta chain (c.-280G>T) polymorphisms and endometriosis in Romanian women.We performed the polymorphic analysis of the FSH receptor gene and FSH beta chain in 44 patients with endometriosis and 34 controls. Genomic DNA was
A, Tanase +5 more
openaire +3 more sources
FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts [PDF]
Cells of the monocyte series respond to follicle stimulating hormone (FSH) by poorly characterized mechanisms. We studied FSH-receptors (FSH-R) and FSH response in nontransformed human monocytes and in osteoclasts differentiated from these cells.
Lisa J, Robinson +8 more
openaire +2 more sources

