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Electrophysiology of ionotropic GABA receptors [PDF]
Cellular and Molecular Life Sciences, 2021 GABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and diverse roles GABAA receptors play in the regulation of neuronal ...
Erwan Sallard +2 more
semanticscholar +5 more sources
BMC Research Notes, 2012 Background GABA receptors are well known as the inhibitory receptors in the central nervous system and are also found in peripheral tissues. We have previously shown that GABA receptors are involved in lung development and fluid homeostasis. However, the
Zhao Chunling +5 more
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Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes. [PDF]
PLoS ONE, 2012 γ-Aminobutyric acid (GABA) is the most prominent neuroinhibitory transmitter in the brain, where it activates neuronal GABA-A receptors (GABA-A channels) located at synapses and outside of synapses.
Suresh K Mendu +3 more
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Cells, 2022 Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by activating the ionotropic GABAA receptors on cerebrovascular endothelial cells ...
Sharon Negri +8 more
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Pharmacological Effect of GABA Analogues on GABA-ϱ2 Receptors and Their Subtype Selectivity
Life, 2022 GABAϱ receptors are distinctive GABAergic receptors from other ionotropic GABAA and metabotropic GABAB receptors in their pharmacological, biochemical, and electrophysiological properties. Although GABA-ϱ1 receptors are the most studied in this subfamily,
Moawiah M. Naffaa +3 more
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Characterization of GABA Receptors [PDF]
Current Protocols in Pharmacology, 1998 AbstractDescribed in this unit are ligand‐binding assays for GABAA, GABAB, and the homomeric ρ GABAA(formerly GABAC) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining these receptors in the CNS.
Kenneth E. McCarson, S.J. Enna
openaire +2 more sources
Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. [PDF]
PLoS ONE, 2011 Together, acid-sensing ion channels (ASICs) and epithelial sodium channels (ENaC) constitute the majority of voltage-independent sodium channels in mammals. ENaC is regulated by a chloride channel, the cystic fibrosis transmembrane conductance regulator (
Xuanmao Chen +3 more
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Axonal Modulation of Striatal Dopamine Release by Local γ-Aminobutyric Acid (GABA) Signalling
Cells, 2021 Striatal dopamine (DA) release is critical for motivated actions and reinforcement learning, and is locally influenced at the level of DA axons by other striatal neurotransmitters. Here, we review a wealth of historical and more recently refined evidence
Bradley M. Roberts +2 more
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Expression and Function of GABA Receptors in Myelinating Cells
Frontiers in Cellular Neuroscience, 2020 Myelin facilitates the fast transmission of nerve impulses and provides metabolic support to axons. Differentiation of oligodendrocyte progenitor cells (OPCs) and Schwann cell (SC) precursors is critical for myelination during development and myelin ...
Mari Paz Serrano-Regal +7 more
semanticscholar +1 more source
Expression of GABAergic receptors in mouse taste receptor cells. [PDF]
PLoS ONE, 2010 Multiple excitatory neurotransmitters have been identified in the mammalian taste transduction, with few studies focused on inhibitory neurotransmitters.
Margaret R Starostik +4 more
doaj +1 more source