Results 31 to 40 of about 449,457 (314)

Stimulation of TM3 Leydig cell proliferation via GABA_A receptors: A new role for testicular GABA

Reproductive Biology and Endocrinology, 2004
The neurotransmitter gamma-aminobutyric acid (GABA) and subtypes of GABA receptors were recently identified in adult testes. Since adult Leydig cells possess both the GABA biosynthetic enzyme glutamate decarboxylase (GAD), as well as GABAA and GABAB ...
Krieger Annette, Thalhammer Andrea, Doepner Richard FG, Geigerseder Christof, Mayerhofer Artur   +4 more
doaj   +1 more source

Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]

, 2014
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Peppiatt-Wildman, Claire M., Wildman, Scott S.P., Dunn, Kadeshia, Kelley, Stephen P., Wildman, Scott S. P.   +4 more
core   +1 more source

The potential role of pancreatic γ-aminobutyric acid (GABA) in diabetes mellitus: A critical reappraisal

International Journal of Preventive Medicine, 2021
Background: Diabetes mellitus (DM) is an endocrine disorder characterized by hyperglycemia, polyuria, polydipsia, and glucosuria. γ-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the central nervous system (CNS) of humans and other mammals.
Hayder M Al-Kuraishy, Nawar R Hussian, Marwa S Al-Naimi, Ali I Al-Gareeb, Farah Al-Mamorri, Ali K Al-Buhadily   +5 more
doaj   +1 more source

Co-operative Effect Between γ-Aminobutyric Acid A Receptors and Central-Type Benzodiazepine Receptors on Amylase Release in Rat Parotid Acinar Cells

Journal of Pharmacological Sciences, 2010
We investigated the inhibitory role of γ-aminobutyric acid A (GABA A ) receptors on amylase release and the evidence for functional coupling with central-type benzodiazepine receptors in rat parotid acinar cells.
Migiwa Okubo, Mitsuru Kawaguchi
doaj   +1 more source

Exploring the Therapeutic Potential of Gamma-Aminobutyric Acid in Stress and Depressive Disorders through the Gut–Brain Axis

Biomedicines, 2023
Research conducted on individuals with depression reveals that major depressive disorders (MDDs) coincide with diminished levels of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) in the brain, as well as modifications in the subunit ...
Timur Liwinski, Undine E. Lang, Annette B. Brühl, Else Schneider   +3 more
doaj   +1 more source

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas, Schwarz, Wolfgang, Xu, Nanjie, Pu, Lu, Pei, Gang, Gu, Quanbao, Xia, Peng, Ren, Shuanglai   +7 more
core   +1 more source

Control of cortical neuronal migration by glutamate and GABA

Frontiers in Cellular Neuroscience, 2015
Neuronal migration in the cortex is controlled by the paracrine action of the classical neurotransmitters glutamate and GABA. Glutamate controls radial migration of pyramidal neurons by acting primarily on NMDA receptors and regulates tangential ...
Heiko J Luhmann, Werner eKilb, Atsuo eFukuda   +2 more
doaj   +1 more source

Activation of the Rat α1β2ε GABA_A Receptor by Orthosteric and Allosteric Agonists

Biomolecules, 2022
GABAA receptors are a major contributor to fast inhibitory neurotransmission in the brain. The receptors are activated upon binding the transmitter GABA or allosteric agonists including a number of GABAergic anesthetics and neurosteroids.
Allison L. Germann, Ariel B. Burbridge, Spencer R. Pierce, Gustav Akk   +3 more
doaj   +1 more source

Role of GABA and its receptors in anti-adipogenesis in cultured adipocytes [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2020
Health benefits of GABA and GABA-enriched foods via anti-obesity activity have been demonstrated in animals. However, the functional roles of GABA especially as non-neurotransmitter in adipocytes have not been thoroughly clarified.
Kanittaporn Trisat, Saowalak Yomlar, Nanteetip Limpeanchob   +2 more
doaj   +1 more source

Neurosteroids and GABA-A Receptor Function [PDF]

Frontiers in Endocrinology, 2011
Neurosteroids represent a class of endogenous steroids that are synthesized in the brain, the adrenals, and the gonads and have potent and selective effects on the GABAA-receptor. 3α-hydroxy A-ring reduced metabolites of progesterone, deoxycorticosterone, and testosterone are positive modulators of GABA(A)-receptor in a non-genomic manner ...
openaire   +3 more sources