Benzodiazepine-resistant epilepsy: unraveling molecular mechanisms and developing multimodal therapeutic strategies. [PDF]
Huang Y, Zhang Y, Liang Y.
europepmc +1 more source
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo+5 more
wiley +1 more source
Unveiling GABA and Serotonin Interactions During Neurodevelopment to Re-Open Adult Critical Periods for Neuropsychiatric Disorders. [PDF]
Beretta E, Cuboni G, Deidda G.
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Abstract Background The coexistence of tics with Parkinson's disease (PD) is rare, as they often emerge at different ages, follow different trajectories and involve contrasting pathophysiological mechanisms related to dopamine availability and function in the brain. Cases We present 10 individuals with primary tic disorders who later developed PD.
Tarig Abkur+11 more
wiley +1 more source
From the gut to the brain, mechanisms and clinical applications of γ-aminobutyric acid (GABA) on the treatment of anxiety and insomnia. [PDF]
Jiang C, Chen Y, Sun T.
europepmc +1 more source
Whether the Opsoclonus Myoclonus Syndrome Is Paraneoplastic or SARS‐CoV‐2–Related Can Be Clarified
IJU Case Reports, EarlyView.
Josef Finsterer
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Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou+6 more
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GABA and Octopamine Receptors as Potential Targets for Fumigant Actions of <i>Bursera graveolens</i> Essential Oil Against <i>Callosobruchus maculatus</i> and <i>Callosobruchus chinensis</i>. [PDF]
Viteri LO+11 more
europepmc +1 more source
Pathophysiological Role of Primary Motor Cortex in Essential Tremor
Abstract Background Essential tremor (ET) is one of the most prevalent movement disorders. However, the complete understanding of ET pathophysiology remains elusive. Objective To explore the pathophysiological role of primary motor cortex (M1) in ET, specifically exploring its neurophysiological changes and their correlation with voluntary motor ...
Daniele Birreci+10 more
wiley +1 more source