Results 151 to 160 of about 2,453,144 (355)
Molecular and pharmacological characterization of native cortical γ- aminobutyric acids receptors containing both α1 and α3 subunits [PDF]
, 1996 We have investigated the existence, molecular composition, and benzodiazepine binding properties of native cortical α1-α3 γ- aminobutyric acid(A) (GABA(A)) receptors using subunit-specific antibodies. The co-existence of α1 and α3 subunits in native GABA(
Araujo, Francisco +5 more
core
European Journal of Organic Chemistry, EarlyView.The hydroformylation of methyl 4‐chlorocinnamate exhibited either high values for regioselectivity (96 %) or selectivity (78 %) for the β‐aldehyde 2 a depending on pressure, CO/H2 composition and temperature in a design of experiments approach. Expanding the substrate scope gave insights into the structure‐activity relationship revealing a significant ...
Hannah Bork, Harald Gröger
wiley +1 more source
Modeling Retinal Ganglion Cell Population Activity with Restricted Boltzmann Machines [PDF]
arXiv, 2017 The retina is a complex nervous system which encodes visual stimuli before higher order processing occurs in the visual cortex. In this study we evaluated whether information about the stimuli received by the retina can be retrieved from the firing rate distribution of Retinal Ganglion Cells (RGCs), exploiting High-Density 64x64 MEA technology. To this
arxiv
European Journal of Organic Chemistry, EarlyView.In an environmentally friendly process for synthesizing heterocyclic molecules of therapeutic interest, imidazo[1,2‐a]pyridine, imidazo[1,2‐a]pyrazine and imidazo[1,2‐b]pyridazine core structures are obtained by a multicomponent Groebke–Blackburn–Bienaymé reaction using bio‐based recyclable solvents.
Abdelkarim El Qami +5 more
wiley +1 more source
Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells
EBioMedicine, 2018 In human pancreatic islets, the neurotransmitter γ-aminobutyric acid (GABA) is an extracellular signaling molecule synthesized by and released from the insulin-secreting β cells.
Sergiy V. Korol +10 more
doaj
Frontiers in Physiology, 2018 γ-Aminobutyric Acid (GABA) and its receptors, GABAA,B,C, are expressed in several locations along the gastrointestinal tract. Nevertheless, a role for GABA in enteric synaptic transmission remains elusive.
Katerina Koussoulas +4 more
doaj +1 more source
The role of GABA-B in sensorigating processing disorders in rat models, an autoradiographic study [PDF]
, 2019 INTRODUCTION: The process of sensorimotor gating is a neurological phenomenon referring to the brain’s ability to process and filter out stimuli in order to prevent an overflow of information.
Zhuang, Alex
core
Monitoring Addiction to Pregabalin in Northern Algeria by Using Hair Testing
ELECTROPHORESIS, Volume 46, Issue 5-6, Page 316-321, March 2025.ABSTRACT Pregabalin (PGB) is a novel gamma‐aminobutyric acid analog that has been recently approved for the treatment of partial‐onset seizures, neuropathic pain, and fibromyalgia. Although PGB presents a low potential for abuse in comparison to other scheduled drugs, the literature reports its potential misuse, especially among individuals with former
Tehami Soumia +5 more
wiley +1 more source
A new characterization of partial metric completeness [PDF]
arXiv, 2019 In this article, we present a new characterization of the completeness of a partial metric space--which we call \textit{orbital characterization}-- using fixed point results.
arxiv
The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABA$_{B}$ receptors under ischemic conditions by inhibiting fast receptor recycling [PDF]
GABA$_{B}$ receptors mediate prolonged inhibition in the brain and are important for keeping neuronal excitation and inhibition in a healthy balance. However, under excitotoxic/ischemic conditions, GABA$_{B}$ receptors are downregulated by dysregulated ...
Benke, Dietmar +4 more
core +1 more source