Results 211 to 220 of about 2,453,144 (355)

Role of γ-Aminobutyric Acid (GABA) as an Inhibitory Neurotransmitter in Diabetes Management: Mechanisms and Therapeutic Implications. [PDF]

Biomolecules
Barakat H, Aljutaily T.
europepmc   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

Pleiotropic neurotransmitters: neurotransmitter-receptor crosstalk regulates excitation-inhibition balance in social brain functions and pathologies. [PDF]

Front Neurosci
Chai A.
europepmc   +1 more source

Pathophysiological Role of Primary Motor Cortex in Essential Tremor

Movement Disorders, EarlyView.
Abstract Background Essential tremor (ET) is one of the most prevalent movement disorders. However, the complete understanding of ET pathophysiology remains elusive. Objective To explore the pathophysiological role of primary motor cortex (M1) in ET, specifically exploring its neurophysiological changes and their correlation with voluntary motor ...
Daniele Birreci, Luca Angelini, Giulia Paparella, Davide Costa, Antonio Cannavacciuolo, Massimiliano Passaretti, Martina De Riggi, Simone Aloisio, Donato Colella, Andrea Guerra, Matteo Bologna   +10 more
wiley   +1 more source

Proteostasis regulation of GABA_A receptors in neuronal function and disease. [PDF]

Biomed Pharmacother
Chen X, Wang YJ, Mu TW.
europepmc   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

Huyang Yangkun Formula Enhances Ovarian Function and Delays Reproductive Aging by Influencing Hypothalamic GnRH/LH Pulse Release Through GAT-1/GABA/GABAAR2. [PDF]

Drug Des Devel Ther
Li Y, Peng Y, Nie G, Cheng F, Zhou Y, Liu J, Yang H.   +6 more
europepmc   +1 more source

GABA and benzodiazepine receptors [PDF]

Nature, 1978
openaire   +2 more sources

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

Medicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva, Carlo Matera, Silvia Roda, Alessio Colleoni, Marco De Amici, Pau Gorostiza   +5 more
wiley   +1 more source

Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels. [PDF]

Sci Rep
Hadadi M, Farazi MM, Mehrabani M, Tashakori-Miyanroudi M, Behroozi Z.   +4 more
europepmc   +1 more source