Results 41 to 50 of about 2,530,726 (346)
Journal of Neuroscience, 1999 To understand the functional significance and mechanisms of action in the CNS of endogenous and exogenous cannabinoids, it is crucial to identify the neural elements that serve as the structural substrate of these actions.
I. Katona +6 more
semanticscholar +1 more source
International Journal of Preventive Medicine, 2021 Background: Diabetes mellitus (DM) is an endocrine disorder characterized by hyperglycemia, polyuria, polydipsia, and glucosuria. γ-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the central nervous system (CNS) of humans and other mammals.
Hayder M Al-Kuraishy +5 more
doaj +1 more source
GABA potency at GABAA receptors found in synaptic and extrasynaptic zones
Frontiers in Cellular Neuroscience, 2012 The potency of GABA is vitally important for its primary role in activating GABAA receptors and acting as an inhibitory neurotransmitter. Although numerous laboratories have presented information, directly or indirectly, on GABA potency, it is often ...
Martin eMortensen +2 more
doaj +1 more source
Role of GABA and its receptors in anti-adipogenesis in cultured adipocytes [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2020 Health benefits of GABA and GABA-enriched foods via anti-obesity activity have been demonstrated in animals. However, the functional roles of GABA especially as non-neurotransmitter in adipocytes have not been thoroughly clarified.
Kanittaporn Trisat +2 more
doaj +1 more source
Emerging neurotrophic role of GABAB receptors in neuronal circuit development [PDF]
, 2013 The proper development of highly organized structures in the central nervous system is a complex process during which key events – neurogenesis, migration, growth, differentiation, and synaptogenesis – have to take place in an appropriate manner to ...
Christophe Porcher, Jean-Luc Gaiarsa
core +1 more source
Journal of Pharmacological Sciences, 2010 We investigated the inhibitory role of γ-aminobutyric acid A (GABA A ) receptors on amylase release and the evidence for functional coupling with central-type benzodiazepine receptors in rat parotid acinar cells.
Migiwa Okubo, Mitsuru Kawaguchi
doaj +1 more source
Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus [PDF]
, 2005 Persistent activation of GABAA receptors by extracellular GABA (tonic inhibition) plays a critical role in signal processing and network excitability in the brain.
Kullmann, D.M. +4 more
core +1 more source
Modulation of the GABAergic pathway for the treatment of fragile X syndrome. [PDF]
, 2014 Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most common single-gene cause of autism. It is caused by mutations on the fragile X mental retardation gene (FMR1) and lack of fragile X mental retardation ...
Hagerman, Randi J +2 more
core +1 more source
Control of cortical neuronal migration by glutamate and GABA
Frontiers in Cellular Neuroscience, 2015 Neuronal migration in the cortex is controlled by the paracrine action of the classical neurotransmitters glutamate and GABA. Glutamate controls radial migration of pyramidal neurons by acting primarily on NMDA receptors and regulates tangential ...
Heiko J Luhmann +2 more
doaj +1 more source
Children, 2022 Gamma-amino butyric acid (GABA) is well known to help elevate pancreatic β cell vitality and insulin levels in blood. GABA works via a coupling with GABA receptors; thus, the concentration of GABAA receptors on the plasma membrane of β cells appears to ...
Eung-Kwon Pae +2 more
doaj +1 more source