Results 11 to 20 of about 57,541 (162)

Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo. [PDF]

PLoS ONE, 2017
Ghrelin is a peptide hormone produced mainly in the gastrointestinal tract known to regulate several physiological functions including gut motility, adipose tissue accumulation and hunger sensation leading to increased bodyweight.
Maria Barington, Marianne Møller Brorson, Jacob Hofman-Bang, Åse Krogh Rasmussen, Birgitte Holst, Ulla Feldt-Rasmussen   +5 more
doaj   +1 more source

Gonadotropin-Releasing Hormone and Its Role in the Enteric Nervous System

Frontiers in Endocrinology, 2017
Gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone, and luteinizing hormone orchestrate the reproduction cycle and regulate the sex steroid secretion from the gonads.
Bodil Ohlsson, Bodil Ohlsson
doaj   +1 more source

Neuroimmune connections between corticotropin-releasing hormone and mast cells: novel strategies for the treatment of neurodegenerative diseases

Neural Regeneration Research, 2021
Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis, which plays a major role in the body’s immune response to stress.
Piplu Bhuiyan, Yi-Wei Wang, Huan-Huan Sha, Hong-Quan Dong, Yan-Ning Qian   +4 more
doaj   +1 more source

Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control

Frontiers in Endocrinology, 2018
The gastrointestinal tract stores ingested nutrients in the stomach which are then delivered to the small intestine at a controlled rate to optimize their digestion and absorption. The interaction of nutrients with the small and large intestine generates
Cong Xie, Xuyi Wang, Xuyi Wang, Richard L. Young, Richard L. Young, Michael Horowitz, Christopher K. Rayner, Tongzhi Wu, Tongzhi Wu   +8 more
doaj   +1 more source

Short-chain fatty acids, secondary bile acids and indoles: gut microbial metabolites with effects on enteroendocrine cell function and their potential as therapies for metabolic disease

Frontiers in Endocrinology, 2023
The gastrointestinal tract hosts the largest ecosystem of microorganisms in the body. The metabolism of ingested nutrients by gut bacteria produces novel chemical mediators that can influence chemosensory cells lining the gastrointestinal tract ...
Karly E. Masse, Van B. Lu
doaj   +1 more source

Possible Relationship between Long-Term Adverse Health Effects of Gonad-Removing Surgical Sterilization and Luteinizing Hormone in Dogs

Animals, 2020
Spaying and neutering dogs is commonly used to prevent the birth of unwanted animals and eliminate the risk of reproductive diseases. However, removal of the gonads prevents the feedback of estrogen and testosterone on the pituitary and hypothalamus.
Michelle A. Kutzler
doaj   +1 more source

Gastrointestinal effects of incretin hormone receptor agonists

Clinical Endocrinology and Endocrine Surgery
Agonists of incretin receptors (AIRs), such as glucagon‑like peptide‑1 (GLP‑1) and glucose‑dependent insulinotropic peptide (GIP), are widely used in the complex treatment of type 2 diabetes mellitus (T2DM) and obesity worldwide. To date, there are 7 AIRs approved by the FDA and available for clinical use.
S. M. Tkach, O. E. Tretyak, V. B. Dogotar   +2 more
openaire   +3 more sources

Drug-induced diabetes type 2: In silico study involving class B GPCRs.

PLoS ONE, 2019
A disturbance of glucose homeostasis leading to type 2 diabetes mellitus (T2DM) is one of the severe side effects that may occur during a prolonged use of many drugs currently available on the market.
Dorota Latek, Ewelina Rutkowska, Szymon Niewieczerzal, Judyta Cielecka-Piontek   +3 more
doaj   +1 more source

Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats

Molecules, 2021
This study investigated the laxative effects of phlorotannins (Pt) derived from Ecklonia cava (E. cave) on chronic constipation by evaluating alterations in stool parameters, gastrointestinal motility, histopathological structure, mucin secretion ...
Ji-Eun Kim, Yun-Ju Choi, Su-Jin Lee, Jeong-Eun Gong, You-Jung Jin, So-Hae Park, Hee-Seob Lee, Young-Whan Choi, Jin-Tae Hong, Dae-Youn Hwang   +9 more
doaj   +1 more source

Melatonin – apleiotropic hormone

Pediatria i Medycyna Rodzinna, 2016
Melatonin, a tryptophan derivative, is synthesised in mammals mainly in the pineal gland. It coordinates the biological clock by regulating the circadian rhythm. Its production is dependent on light and its concentrations change with age. Thanks to its
Maciej Brzęczek, Karina Słonka, Lidia Hyla-Klekot   +2 more
doaj   +1 more source