The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy
Molecules, 2022 5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, Dagmara Mirowska-Guzel
doaj +1 more source
A novel potential role of pituitary gonadotropins in the pathogenesis of human colorectal cancer. [PDF]
PLoS ONE, 2018 Colorectal cancer (CRC) is a leading cause of death in the western world, and its incidence increases with patient age. It is also known that with age there occur changes in the levels of certain hormones, including an increase in the secretion of ...
Wojciech Marlicz +6 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Hypercalcemia is a common complication in cancer patients Mainly caused by Parathyroid hormone-related protein (PTHrP) secretion and metastasis. Calcitriol secretion is a rare source of hypercalcemia in solid tumors, especially in gastrointestinal ...
Yiraldine Herrera-Martínez +22 more
doaj +1 more source
Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo. [PDF]
PLoS ONE, 2017 Ghrelin is a peptide hormone produced mainly in the gastrointestinal tract known to regulate several physiological functions including gut motility, adipose tissue accumulation and hunger sensation leading to increased bodyweight.
Maria Barington +5 more
doaj +1 more source
Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion [PDF]
, 2010 Context: Glucagon-like peptide-1 (GLP-1) is produced by specialized cells in the gut and secreted in response to carbohydrates and lipids. The mechanisms regulating fat-stimulated GLP-1 release have, however, not been clarified in detail.
Schirra, Joerg +5 more
core +1 more source
Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
, 2013 The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre +7 more
core +1 more source
Expression and distribution of GnRH, LH, and FSH and their receptors in gastrointestinal tract of man and rat. [Elektronisk resurs] [PDF]
, 2013 Gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) regulate the reproductive axis. Their analogs have been found to influence gastrointestinal activity and enteric neuronal survival.
Bergvall, Monika +5 more
core +4 more sources
Neural Regeneration Research, 2021 Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis, which plays a major role in the body’s immune response to stress.
Piplu Bhuiyan +4 more
doaj +1 more source
Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control
Frontiers in Endocrinology, 2018 The gastrointestinal tract stores ingested nutrients in the stomach which are then delivered to the small intestine at a controlled rate to optimize their digestion and absorption. The interaction of nutrients with the small and large intestine generates
Cong Xie +8 more
doaj +1 more source
Frontiers in Endocrinology, 2023 The gastrointestinal tract hosts the largest ecosystem of microorganisms in the body. The metabolism of ingested nutrients by gut bacteria produces novel chemical mediators that can influence chemosensory cells lining the gastrointestinal tract ...
Karly E. Masse, Van B. Lu
doaj +1 more source