Results 11 to 20 of about 62,827 (261)
Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis [PDF]
Experimental and Molecular Medicine, 2018 Stomach cancer: DNA methylation of hormone receptor genes A sequencing study reveals abnormal changes to DNA that set the stage for stomach cancer development.
Hee-Jin Kim +9 more
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Neural Regeneration Research, 2021 Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis, which plays a major role in the body’s immune response to stress.
Piplu Bhuiyan +4 more
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Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control
Frontiers in Endocrinology, 2018 The gastrointestinal tract stores ingested nutrients in the stomach which are then delivered to the small intestine at a controlled rate to optimize their digestion and absorption. The interaction of nutrients with the small and large intestine generates
Cong Xie +8 more
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Frontiers in Endocrinology, 2023 The gastrointestinal tract hosts the largest ecosystem of microorganisms in the body. The metabolism of ingested nutrients by gut bacteria produces novel chemical mediators that can influence chemosensory cells lining the gastrointestinal tract ...
Karly E. Masse, Van B. Lu
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Drug-induced diabetes type 2: In silico study involving class B GPCRs.
PLoS ONE, 2019 A disturbance of glucose homeostasis leading to type 2 diabetes mellitus (T2DM) is one of the severe side effects that may occur during a prolonged use of many drugs currently available on the market.
Dorota Latek +3 more
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Animals, 2020 Spaying and neutering dogs is commonly used to prevent the birth of unwanted animals and eliminate the risk of reproductive diseases. However, removal of the gonads prevents the feedback of estrogen and testosterone on the pituitary and hypothalamus.
Michelle A. Kutzler
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Molecules, 2021 This study investigated the laxative effects of phlorotannins (Pt) derived from Ecklonia cava (E. cave) on chronic constipation by evaluating alterations in stool parameters, gastrointestinal motility, histopathological structure, mucin secretion ...
Ji-Eun Kim +9 more
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Melatonin – apleiotropic hormone
Pediatria i Medycyna Rodzinna, 2016 Melatonin, a tryptophan derivative, is synthesised in mammals mainly in the pineal gland. It coordinates the biological clock by regulating the circadian rhythm. Its production is dependent on light and its concentrations change with age. Thanks to its
Maciej Brzęczek +2 more
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Gastrointestinal neurotensin receptors: lack of modulation by thyrotropin releasing hormone
Journal of Pharmacy and Pharmacology, 1985 AbstractTo examine whether thyrotropin releasing hormone (TRH) antagonized gastrointestinal neurotensin receptors in isolated segments of the rat fundus, duodenum and ileum, tissues were superfused, mounted and the isometric tension recorded. Picomoles of neurotensin caused concentration-dependent contractions of the fundus and relaxation of the smooth
M V, Donoso, J P, Huidobro-Toro
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Structure and Physiological Actions of Ghrelin
Scientifica, 2013 Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n-octanoylation modification on its serine in position 3, catalyzed by ghrelin
Christine Delporte
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