Results 21 to 30 of about 57,541 (162)

Gastrointestinal neurotensin receptors: lack of modulation by thyrotropin releasing hormone

open access: yesJournal of Pharmacy and Pharmacology, 1985
AbstractTo examine whether thyrotropin releasing hormone (TRH) antagonized gastrointestinal neurotensin receptors in isolated segments of the rat fundus, duodenum and ileum, tissues were superfused, mounted and the isometric tension recorded. Picomoles of neurotensin caused concentration-dependent contractions of the fundus and relaxation of the smooth
M V, Donoso, J P, Huidobro-Toro
openaire   +2 more sources

Structure and Physiological Actions of Ghrelin

open access: yesScientifica, 2013
Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n-octanoylation modification on its serine in position 3, catalyzed by ghrelin
Christine Delporte
doaj   +1 more source

Metastatic Lobular Breast Cancer Mimicking Colitis

open access: yesReports, 2020
Breast cancer is the most frequent cancer diagnosed in women in the world regardless of race or ethnicity. About 10% of invasive breast carcinomas are lobular subtype.
Renata Reis Figueiredo   +3 more
doaj   +1 more source

Enteroendocrine cell regulation of the gut-brain axis

open access: yesFrontiers in Neuroscience, 2023
Enteroendocrine cells (EECs) are an essential interface between the gut and brain that communicate signals about nutrients, pain, and even information from our microbiome.
Joshua R. Barton   +6 more
doaj   +1 more source

Bitter taste receptors influence glucose homeostasis. [PDF]

open access: yesPLoS ONE, 2008
TAS1R- and TAS2R-type taste receptors are expressed in the gustatory system, where they detect sweet- and bitter-tasting stimuli, respectively. These receptors are also expressed in subsets of cells within the mammalian gastrointestinal tract, where they
Cedrick D Dotson   +13 more
doaj   +1 more source

Gastric metastasis of breast cancer: a case series

open access: yesRare Tumors, 2016
Gastric metastasis is rare but it can be the initial symptom of cancer. The second leading cause of this type of metastasis is breast cancer. A lack of clinical signs and nonspecific side effects of the treatment of primary tumors can lead to the ...
Gustavo dos Santos Fernandes   +5 more
doaj   +1 more source

Receptors for Gastrointestinal Hormones

open access: yesGastroenterology, 1979
The success of this paper will be measured by the extent to which it provides information that will enable the reader to evaluate critically a paper dealing with receptors for gastrointestinal or other hormones. The paper has two parts. Part I deals with technical and conceptual aspects of hormone action that bear on the design, execution ...
openaire   +2 more sources

Urocortins in the mammalian endocrine system

open access: yesActa Veterinaria Scandinavica, 2019
Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family, are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body functions by binding to two G protein-coupled receptors: receptor type 1 ...
Caterina Squillacioti   +3 more
doaj   +1 more source

Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013
Foregut neuroendocrine tumors [NETs] usually pursuit a benign course, but some show aggressive behavior. The treatment of patients with advanced NETs is marginally effective and new approaches are needed. In other tumors, transactivation of the EGF receptor (EGFR) by growth factors, gastrointestinal (GI) hormones and lipids can stimulate growth, which ...
Di Florio, Alessia   +4 more
openaire   +2 more sources

Roles of Cholecystokinin in the Nutritional Continuum. Physiology and Potential Therapeutics

open access: yesFrontiers in Endocrinology, 2021
Cholecystokinin is a gastrointestinal peptide hormone with important roles in metabolic physiology and the maintenance of normal nutritional status, as well as potential roles in the prevention and management of obesity, currently one of the dominant ...
Laurence J. Miller   +3 more
doaj   +1 more source

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