Results 21 to 30 of about 57,541 (162)
Gastrointestinal neurotensin receptors: lack of modulation by thyrotropin releasing hormone
AbstractTo examine whether thyrotropin releasing hormone (TRH) antagonized gastrointestinal neurotensin receptors in isolated segments of the rat fundus, duodenum and ileum, tissues were superfused, mounted and the isometric tension recorded. Picomoles of neurotensin caused concentration-dependent contractions of the fundus and relaxation of the smooth
M V, Donoso, J P, Huidobro-Toro
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Structure and Physiological Actions of Ghrelin
Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n-octanoylation modification on its serine in position 3, catalyzed by ghrelin
Christine Delporte
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Metastatic Lobular Breast Cancer Mimicking Colitis
Breast cancer is the most frequent cancer diagnosed in women in the world regardless of race or ethnicity. About 10% of invasive breast carcinomas are lobular subtype.
Renata Reis Figueiredo +3 more
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Enteroendocrine cell regulation of the gut-brain axis
Enteroendocrine cells (EECs) are an essential interface between the gut and brain that communicate signals about nutrients, pain, and even information from our microbiome.
Joshua R. Barton +6 more
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Bitter taste receptors influence glucose homeostasis. [PDF]
TAS1R- and TAS2R-type taste receptors are expressed in the gustatory system, where they detect sweet- and bitter-tasting stimuli, respectively. These receptors are also expressed in subsets of cells within the mammalian gastrointestinal tract, where they
Cedrick D Dotson +13 more
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Gastric metastasis of breast cancer: a case series
Gastric metastasis is rare but it can be the initial symptom of cancer. The second leading cause of this type of metastasis is breast cancer. A lack of clinical signs and nonspecific side effects of the treatment of primary tumors can lead to the ...
Gustavo dos Santos Fernandes +5 more
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Receptors for Gastrointestinal Hormones
The success of this paper will be measured by the extent to which it provides information that will enable the reader to evaluate critically a paper dealing with receptors for gastrointestinal or other hormones. The paper has two parts. Part I deals with technical and conceptual aspects of hormone action that bear on the design, execution ...
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Urocortins in the mammalian endocrine system
Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family, are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body functions by binding to two G protein-coupled receptors: receptor type 1 ...
Caterina Squillacioti +3 more
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Foregut neuroendocrine tumors [NETs] usually pursuit a benign course, but some show aggressive behavior. The treatment of patients with advanced NETs is marginally effective and new approaches are needed. In other tumors, transactivation of the EGF receptor (EGFR) by growth factors, gastrointestinal (GI) hormones and lipids can stimulate growth, which ...
Di Florio, Alessia +4 more
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Roles of Cholecystokinin in the Nutritional Continuum. Physiology and Potential Therapeutics
Cholecystokinin is a gastrointestinal peptide hormone with important roles in metabolic physiology and the maintenance of normal nutritional status, as well as potential roles in the prevention and management of obesity, currently one of the dominant ...
Laurence J. Miller +3 more
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