Results 41 to 50 of about 57,541 (162)

Polypeptide hormone receptors in vivo: demonstration of insulin binding to adrenal gland and gastrointestinal epithelium by quantitative radioautography. [PDF]

Journal of Histochemistry & Cytochemistry, 1980
A tissue-screening survey employing quantitative radioautography was carried out at 2 min after the intravascular injection of 125I-insulin into laboratory rats. The results revealed a substantial binding of insulin to cells forming the proximal convoluted tubule in kidney, hepatocytes of liver, acinar cells of the pancreas, parenchymal cells of the ...
J J, Bergeron, R, Rachubinski, N, Searle, D, Borts, R, Sikstrom, B I, Posner   +5 more
openaire   +2 more sources

Why is motilin active in some studies with mice, rats, and guinea pigs, but not in others? Implications for functional variability among rodents

Pharmacology Research & Perspectives, 2022
The gastrointestinal (GI) hormone motilin helps control human stomach movements during hunger and promotes hunger. Although widely present among mammals, it is generally accepted that in rodents the genes for motilin and/or its receptor have undergone ...
Gareth J. Sanger
doaj   +1 more source

Gastrointestinal Spatiotemporal mRNA Expression of Ghrelin vs Growth Hormone Receptor and New Growth Yield Machine Learning Model Based on Perturbation Theory [PDF]

Scientific Reports, 2016
AbstractThe management of ruminant growth yield has economic importance. The current work presents a study of the spatiotemporal dynamic expression ofGhrelinandGHRat mRNA levels throughout the gastrointestinal tract (GIT) of kid goats under housing and grazing systems.
Ran, Tao, Liu, Yong, Li, Hengzhi, Tang, Shaoxun, He, Zhixiong, Munteanu, Cristian-Robert, González-Díaz, Humberto, Tan, Zhiliang, Zhou, Chuanshe   +8 more
openaire   +3 more sources

Orexigenic hormone ghrelin attenuates local and remote organ injury after intestinal ischemia-reperfusion. [PDF]

PLoS ONE, 2008
Gut ischemia/reperfusion (I/R) injury is a serious condition in intensive care patients. Activation of immune cells adjacent to the huge endothelial cell surface area of the intestinal microvasculature produces initially local and then systemic ...
Rongqian Wu, Weifeng Dong, Youxin Ji, Mian Zhou, Corrado P Marini, Thanjavur S Ravikumar, Ping Wang   +6 more
doaj   +1 more source

Gastrointestinal Hormones Cause Rapid c-Met Receptor Down-regulation by a Novel Mechanism Involving Clathrin-mediated Endocytosis and a Lysosome-dependent Mechanism [PDF]

Journal of Biological Chemistry, 2006
The activated c-Met receptor has potent effects on normal tissues and tumors. c-Met levels are regulated by hepatocyte growth factor (HGF); however, it is unknown if they can be regulated by gastrointestinal (GI) hormones. c-Met is found in many GI tissues/tumors that possess GI hormone receptors.
K Martin, Hoffmann, Jose A, Tapia, Marc J, Berna, Michelle, Thill, Till, Braunschweig, Samuel A, Mantey, Terry W, Moody, Robert T, Jensen   +7 more
openaire   +2 more sources

Multi-scale simulations of membrane proteins: The case of bitter taste receptors

Journal of Science: Advanced Materials and Devices, 2017
Human bitter taste receptors (hTAS2Rs) are the second largest group of chemosensory G-protein coupled receptors (25 members). hTAS2Rs are expressed in many tissues (e.g.
Eda Suku, Fabrizio Fierro, Alejandro Giorgetti, Mercedes Alfonso-Prieto, Paolo Carloni   +4 more
doaj   +1 more source

Metabolic Regulation by the Hypothalamic Neuropeptide, Gonadotropin-Inhibitory Hormone at Both the Central and Peripheral Levels

Cells
Gonadotropin-inhibitory hormone (GnIH) is well-established as a negative regulator of reproductive physiology and behavior across vertebrates, acting on the hypothalamic–pituitary–gonadal (HPG) axis; however, recent data have also demonstrated its ...
You Lee Son, Simone L. Meddle, Yasuko Tobari   +2 more
doaj   +1 more source

Insulin-like Growth Factors (IGFs) and their binding proteins (IGFBPs) as biomarkers of catabolism [PDF]

Journal of Medical Biochemistry, 2007
The life of an organism depends on its capacity to maintain equilibrium Disease induces acute adaptive responses specific to the stimulus and the organism achieves stability through change.
Nedić Olgica, Nikolić-Judith Anna, Malenković Vesna, Baričević-Jones Ivona   +3 more
doaj  

Functional engineering of human iPSC‐derived parasympathetic neurons enhances responsiveness to gastrointestinal hormones

FEBS Open Bio
Food‐derived biological signals are transmitted to the brain via peripheral nerves through the paracrine activity of gastrointestinal (GI) hormones. The signal transduction circuit of the brain–gut axis has been analyzed in animals; however, species ...
Yuka Akagi, Yuzo Takayama, Yuma Nihashi, Azusa Yamashita, Risa Yoshida, Yasuhisa Miyamoto, Yasuyuki S. Kida   +6 more
doaj   +1 more source

Tannin alleviated reproductive dysfunction in pregnant ewes infected with Haemonchus contortus

Frontiers in Veterinary Science
IntroductionHaemonchus contortus (H. contortus) infection has a significant impact on the health of pregnant ewes and adversely affects fetal development, highlighting the critical need for a non-toxic feed additive as an alternative and sustainable ...
Xin Li, Xin Li, Hai Xiang, Hai Xiang, Rong Liang, Rong Liang, Xinyu Han, Xinyu Han, Rongzhen Zhong, Rongzhen Zhong, Hongyu Liu, Hongyu Liu, Yi Fang, Yi Fang   +13 more
doaj   +1 more source