Results 31 to 40 of about 29,825 (276)

Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats [PDF]

open access: yes, 2014
We thank Donna Wallace and the Rowett Animal House staff for the daily care of experimental rats, body weight and food intake measurements and MRI scanning, Vivien Buchan and Donna Henderson of the Rowett Analytical Department for proximate analyses and ...
Adam, Clare L   +7 more
core   +2 more sources

Gut ghrelin regulates hepatic glucose production and insulin signaling via a gut-brain-liver pathway

open access: yesCell Communication and Signaling, 2019
Background Ghrelin modulates many physiological processes. However, the effects of intestinal ghrelin on hepatic glucose production (HGP) are still unclear.
Yao Lin   +10 more
doaj   +1 more source

Why is motilin active in some studies with mice, rats, and guinea pigs, but not in others? Implications for functional variability among rodents

open access: yesPharmacology Research & Perspectives, 2022
The gastrointestinal (GI) hormone motilin helps control human stomach movements during hunger and promotes hunger. Although widely present among mammals, it is generally accepted that in rodents the genes for motilin and/or its receptor have undergone ...
Gareth J. Sanger
doaj   +1 more source

Is fat the sixth taste primary? Evidence and implications [PDF]

open access: yes, 2015
Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Andrew Costanzo, Russell Keast
core   +1 more source

Pancreatic exocrine insufficiency after bariatric surgery [PDF]

open access: yes, 2017
Morbid obesity is a lifelong disease, and all patients require complementary follow-up including nutritional surveillance by a multidisciplinary team after bariatric procedures.
Arnelo, Urban   +7 more
core   +1 more source

Ghrelin, via corticotropin‐releasing factor receptors, reduces glucose uptake and increases lipid content in mouse myoblasts cells

open access: yesPhysiological Reports, 2021
Ghrelin and the corticotropin‐releasing factor (CRF) family are known regulators of cellular metabolism and energy balance. We previously demonstrated that myoblast glucose metabolism is regulated by ghrelin and that this effect is mediated by CRF ...
Michal Elbaz, Eran Gershon
doaj   +1 more source

Neuropeptide receptors as potential antiepileptic drug targets : focus on the ghrelin axis [PDF]

open access: yes, 2014
Epilepsy is a very serious neurological disorder which is often underrepresented. Around 50 million individuals worldwide have active epilepsy with recurrent seizures and in spite of the medical advances over the years, 30% of these patients remain as ...
Portelli, Jeanelle
core   +1 more source

Cannabinoids enhance gastric X/A-like cells activity.

open access: yesFolia Histochemica et Cytobiologica, 2008
It has been reported that cannabinoids may cause overeating in humans and in laboratory animals. Although, endogenous cannabinoids and their receptors (CB1) have been found in the hypothalamus, and recently also in gastrointestinal tract, the precise ...
Bogusław Sawicki   +3 more
doaj   +1 more source

Ghrelin cell–expressed insulin receptors mediate meal- and obesity-induced declines in plasma ghrelin

open access: yesJCI Insight, 2021
Mechanisms underlying postprandial and obesity-associated plasma ghrelin reductions are incompletely understood. Here, using ghrelin cell–selective insulin receptor–KO (GhIRKO) mice, we tested the impact of insulin, acting via ghrelin cell–expressed ...
Kripa Shankar   +9 more
doaj   +1 more source

Allosteric modulation of ghrelin receptor signaling by lipids [PDF]

open access: yesNature Communications, 2021
AbstractThe membrane is an integral component of the G protein-coupled receptor signaling machinery. Here we demonstrate that lipids regulate the signaling efficacy and selectivity of the ghrelin receptor GHSR through specific interactions and bulk effects.
Damian, Marjorie   +11 more
openaire   +3 more sources

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