Results 31 to 40 of about 45,803 (309)
Role of histamine H3 receptor in glucagon‐secreting αTC1.6 cells
FEBS Open Bio, 2015 Pancreatic α‐cells secrete glucagon to maintain energy homeostasis. Although histamine has an important role in energy homeostasis, the expression and function of histamine receptors in pancreatic α‐cells remains unknown.
Tadaho Nakamura +7 more
doaj +1 more source
Does glucagon have a positive inotropic effect in the human heart?
Cardiovascular Diabetology, 2018 Glucagon is considered to exert cardiostimulant effects, most notably the enhancement of heart rate and contractility, due to the stimulation of glucagon receptors associated with Gs protein stimulation which causes adenylyl cyclase activation and the ...
Jesus Hernández-Cascales
doaj +1 more source
An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]
, 2002 There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C. +5 more
core +1 more source
Potential Therapeutic Targeting Neurotransmitter Receptors in Diabetes
Frontiers in Endocrinology, 2022 Neurotransmitters are signaling molecules secreted by neurons to coordinate communication and proper function among different sections in the central neural system (CNS) by binding with different receptors.
Xiaohui Pan +5 more
doaj +1 more source
Tail engagement of arrestin at the glucagon receptor
Nature, 2023 AbstractArrestins have pivotal roles in regulating G protein-coupled receptor (GPCR) signalling by desensitizing G protein activation and mediating receptor internalization1,2. It has been proposed that the arrestin binds to the receptor in two different conformations, ‘tail’ and ‘core’, which were suggested to govern distinct processes of receptor ...
Kun Chen +12 more
openaire +2 more sources
Glucagon can increase force of contraction via glucagon receptors in the isolated human atrium [PDF]
Glucagon can increase the force of contraction (FOC) in, for example, canine hearts. Currently, whether glucagon can also increase the FOC via cAMP-increasing receptors in the human atrium is controversial discussed.
Hofmann, Britt +3 more
core +2 more sources
Dual Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Receptor Agonists
Endocrinology Research and Practice, 2022 Glucagon-like peptide-1 is the most potent incretin secreted from the intestinal tract. It is synthesized by L-cells in the jejunum and distal ileum of the gastrointestinal system.
Dilek Tüzün
doaj
Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance
Molecular Metabolism, 2015 Objective: Glucagon receptor antagonists and humanized glucagon antibodies are currently studied as promising therapies for obesity and type II diabetes.
Mar Quiñones +6 more
doaj +1 more source
Translational Psychiatry, 2021 Dopamine (DA) and norepinephrine (NE) are catecholamines primarily studied in the central nervous system that also act in the pancreas as peripheral regulators of metabolism.
Despoina Aslanoglou +15 more
doaj +1 more source
Glucagon receptor number and the MHC [PDF]
Nature, 1986 Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/62898/1/323586b0 ...
openaire +3 more sources