Results 211 to 220 of about 90,980 (312)

A mini-review of chronic suppression of the hypothalamic-pituitary-adrenal axis in animals with P-glycoprotein deficiency. [PDF]

J Small Anim Pract
Mealey KL.
europepmc   +1 more source

Differences in SARS‐CoV‐2 Antigen Persistence in Individuals With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A RECOVER‐Adult Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post–acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel, Zoe Swank, Jiaqi Wang, Xiaosong Wang, Lauren A. O'Keeffe, Madison Negron, Liya S. Getachew, Louise L. Hansen, Grace Qian, Alene A. Saavedra, Kevin T. Mueller, Natalie A. Davis, Kathleen M. M. Vanni, Sandria Savage, Julie S. Lam, Zachary S. Wallace, David R. Walt, Jeffrey A. Sparks, on behalf of RECOVER‐Adult   +18 more
wiley   +1 more source

Alpha-1 antitrypsin-glucocorticoid receptor axis: a new pathway in immune modulation. [PDF]

Mol Med
Möhlis K, Held J, Korenbaum E, Wrenger S, Janciauskiene S, Heiker JT.   +5 more
europepmc   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Different Functions of Human Scavenger Receptors BI and BII Overexpressed in a Murine Abdominal Sepsis Model. [PDF]

Biomolecules
Hayase N, Vishnyakova TG, Baranova IN, Bocharov AV, Hu X, Patterson AP, Yuen PST, Eggerman TL, Star RA.   +8 more
europepmc   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo, Dinesh Khanna, Corrado Campochiaro, Vincent Cottin, Fabrizio Luppi, Marco Matucci‐Cerinic, Gianluca Moroncini, Yannick Allanore   +7 more
wiley   +1 more source

A molecular systems architecture of asthma. [PDF]

Front Immunol
Ayyadurai VAS, Deonikar P, Manoharan Y.
europepmc   +1 more source

The role of IgM anti‐acetylated protein antibodies and B cells in the origin of anti‐modified protein autoimmunity in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated (ACPA), anti‐carbamylated (anti‐CarP), and anti‐acetylated (AAPA) protein antibodies. In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role in early immune responses.
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur HLO, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E.M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Cortisol-resistant CAR-NK cells overcome steroid-induced immunosuppression in lung cancer. [PDF]

Signal Transduct Target Ther
Chakraborty S, Pramanik J, Alviter-Raymundo G, Ward CJ, Shaji SK, Yamashita-Kanemaru Y, Ali FAZ, Banik D, Zhang Z, Veiga-Villauriz C, Homer NZM, Simpson J, Laforest S, Tong S, Zhao Q, Roy J, Iqbal M, Morris AC, Chapman MA, Roychoudhuri R, Hussein H, Klenerman D, Saeb-Parsy K, Mahata B.   +23 more
europepmc   +1 more source

Increased plasma microbial tDR‐1 in at‐risk individuals is associated with decreased conversion to clinical rheumatoid arthritis and reduces an in vitro macrophage type 1 interferon response

Arthritis &Rheumatology, Accepted Article.
Background Microbial small RNAs (sRNAs) can regulate human genes. Higher plasma concentrations of microbial tRNA‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anti‐cyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (ARI)
Anastasiia Phothisane, Tulsi K Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L Feser, Jill M Norris, M Kristen Demoruelle, LauraKay Moss, Kevin D Deane, V Michael Holers, Michelle J Ormseth   +11 more
wiley   +1 more source