Results 91 to 100 of about 2,659,590 (353)

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yang   +15 more
wiley   +1 more source

Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]

, 2014
Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean, Maunze, Brian, Phillips, Kailynn A., Resch, Jon M   +3 more
core   +2 more sources

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Glutamate Receptor Signaling in Retina Müller Cells: Plausible Role in Neurodegeneration

Receptors
The retinal network relies on glutamate, the primary excitatory neurotransmitter involved in the visual cycle. Glutamate transactions are carried out by an array of distinct receptors and transporters distributed across both pre- and post-synaptic ...
Bolaji Oyetayo, Yurixy Mendoza-Silva, Temitayo Subair, Luisa C Hernández-Kelly, Marie-Paule Felder-Schmittbuhl, Tatiana N. Olivares-Bañuelos, Arturo Ortega   +6 more
doaj   +1 more source

THE POSSIBILITY OF ADMINISTRATION OF GLUTAMATE RECEPTORS ANTAGONISTS IN THE TREATMENT OF PARKINSON'S DISEASE [PDF]

Research Results in Pharmacology, 2016
Parkinson's disease is the slow-progressing chronic neurodegenerative disease. It caused by the progressive destruction and death of neurons that produce the neurotransmitter dopamine, primarily in the substantia nigra and also in other parts of the ...
Natalya Avdeeva, Vladislava Nikitina, Indira Kochkarova, Anna Litvinova   +3 more
doaj   +3 more sources

Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]

, 2018
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
core   +1 more source

Changes in synaptic transmission and protein expression in the brains of adult offspring after prenatal inhibition of the kynurenine pathway [PDF]

, 2013
During early brain development, N-methyl-d-aspartate (NMDA) receptors are involved in cell migration, neuritogenesis, axon guidance and synapse formation, but the mechanisms which regulate NMDA receptor density and function remain unclear. The kynurenine
Ahn, Al-Hayani, Alberati-Giani, Alexander, Alexander, Alvarez, Angot, Baez, Banerjee, Beal, Breton, Broadstock, Brown, Brown, C.M. Forrest, Cai, Charytoniuk, Chess, Chess, Chess, Chiarugi, Clark, Colonnese, Copeland, Corbo, Couillard-Despres, Cozzi, Cuppini, D. Jerusalinsky, Dave, Dellovade, Dikranian, Dobbing, Dobelis, Drian, du Bois, Dykens, E. Kornisiuk, English, Erhardt, Ernst, Fagiolini, Fatemi, Fazio, Forrest, Forsythe, Friocourt, Gleeson, Gobaille, Goncalves, Guidetti, Guillemin, Guillemin, Gurdon, Harris, Harvey, Heng, Higgins, Higgins, Hilmas, Hiramatsu, Hoffman, Holtze, Hor, Hornig, Huang, Hynes, Ikonomidou, Iwasato, Jin, K. McNair, Kappeler, Kemp, Kerjan, L.G. Darlington, Larson, Leung, M. Pisar, M. Snitcofsky, Martel, Meyer, Miller, Mok, Munn, Myers, N. Gonzalez, Nacher, Nathan, Neale, Neher, Nilsson, Niswender, O.S. Khalil, Okuda, Otis, Ozaki, O’Kane, Palma, Parish, Pena, Perkins, Pfaffl, Pocivavsek, Potter, Prajerova, Rajan, Ramakers, Ramoa, Rodgers, Rosenmund, Röver, Saito, Saviane, Schwarcz, Schwarcz, Shin, Simon, Sims, Spassky, Stone, Stone, Stone, Stone, Stone, Stringer, T.W. Stone, Taleb, Tang, Traiffort, Traiffort, Traiffort, Traynelis, Udin, Ultanir, Vaillant, Vincent, Waldeck, Walker, Wang, Wang, Wierońska, Wu, Xiong, Zucker, Zuckerman   +144 more
core   +2 more sources

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source