Results 191 to 200 of about 2,623,298 (367)

Quantitative electroencephalographic analysis of delirium tremens development following alcohol‐withdrawal seizure based on a small number of male cases

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Considering the complications related to alcohol withdrawal syndrome (AWS) such as seizure, delirium tremens and cardiac arrhythmia, it is important to identify the risk of delirium tremens (DT) following AWS and enhance preventive strategies. We observed the characteristics of quantitative electroencephalography in patients with AWS, specifically who ...
Jee‐Eun Yoon, Heejung Mo, Dong Wook Kim, Hee‐Jin Im   +3 more
wiley   +1 more source

INVESTIGATIONS OF THE STRUCTURE-FUNCTION RELATIONSHIP IN KAINATE RECEPTORS USING FÖRSTER RESONANCE ENERGY TRANSFER [PDF]

, 2019
Kainate receptors belong to the family of ion channels known as the ionotropic glutamate receptors. Ionotropic glutamate receptors mediate the majority of excitatory synaptic transmission, modulate the release of presynaptic glutamate, and facilitate ...
Litwin, Douglas
core   +1 more source

Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex

Neurobiology of Disease, 2007
In addition to the loss of spinal motor neurons, amyotrophic lateral sclerosis (ALS) is also associated with degeneration of corticospinal layer V pyramidal neurons and decreased glutamate transport in the cortex. We characterized the glutamate receptors
Kate C. Young, Daniel S. McGehee, James R. Brorson   +2 more
doaj  

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem, Mohammed A Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan   +6 more
wiley   +1 more source

The Hippocampus Is the Place to Be: Opioid Receptors and LTP

Cell Reports, 2019
Nam et al. (2019) genetically modulate the expression of astrocytic μ-opioid receptors to reveal they are necessary for drug-induced conditioned place preference.
Thomas M. Sanderson, John Georgiou, Patrick Tidball, Graham L. Collingridge   +3 more
doaj  

Regulation of PVT‐CeA Circuit in Deoxynivalenol‐Induced Anorexia and Aversive‐Like Emotions

Advanced Science, EarlyView.
The study investigates Deoxynivalenol (DON) effects on feeding and emotions, focusing on the central amygdala (CeA). Acute DON exposure reduces food intake and alters behavior, linked to CeAGABA neuron activity and PVT‐CeA connectivity. Manipulating CeAGABA neurons and using SCN10A antagonist A‐803467 alleviate DON's effects, offering potential ...
Liu‐Nan Yang, Mingmeng Tang, Andreas K. Nüssler, Liegang Liu, Wei Yang   +4 more
wiley   +1 more source

Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina [PDF]

, 2005
PURPOSE: Kinetic studies of photoreceptor cell death in the retinal degeneration (rd1) mouse model suggest that photoreceptor degeneration could result from cumulative damage.
Delyfer, MN, Forster, V, Leveillard, T, Neveux, N, Picaud, S, Sahel, JA   +5 more
core  

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

Advanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang, Fangzhou Chen, Nier Wu, Lingfei Hu, Haihua Xiao, Hanchen Zhang, Dongsheng Zhou   +6 more
wiley   +1 more source

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine‐Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms

Advanced Science, EarlyView.
This study uses Caenorhabditis elegans to assess the activity of amphetamine‐type stimulants (ATS) and their analogs. The research highlights the roles of dopamine and serotonin pathways, distinguishes chiral forms of ATS, and identifies structure‐activity relationships. These findings provide a rapid and cost‐effective model for evaluating the effects
Yuanpeng Li, Hongyuan Li, Hongshuang Wang, Xiaohui Wang   +3 more
wiley   +1 more source