Results 221 to 230 of about 310,321 (241)

A comprehensive review of GABA in autism spectrum disorders: associations, mechanisms, and therapeutic implications. [PDF]

Front Psychiatry
Wang P, Sun J.
europepmc   +1 more source

Specific Association Patterns Between Brain Glutathione Levels, Myelination, and Functional Connectivity in Adults With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Recent studies have implicated oxidative stress in the pathophysiology of autism spectrum disorder (ASD). Postmortem brain studies have revealed decreased levels of the reduced form of glutathione (GSH), an important antioxidant, in some brain regions in individuals with ASD; however, in vivo evidence is lacking.
Toshiki Iwabuchi, Takaharu Hirai, Naoko Umeda, Hideto Yogo, Yuuta Nishimiya, Yuuki Nishigaki, Masaru Watanabe, Hidenori Yamasue, Masatsugu Tsujii, Kenji J. Tsuchiya, Hideo Matsuzaki   +10 more
wiley   +1 more source

The Role of Peripheral N-Methyl-D-Asparate (NMDA) Receptors in Itch and Pain: A Narrative Review. [PDF]

Eur J Pain
Tanaka R, Lo Vecchio S, Aliotta GE, Arendt-Nielsen L.   +3 more
europepmc   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

The Active Astrocyte: Calcium Dynamics, Circuit Modulation, and Targets for Intervention. [PDF]

Neurochem Res
Rusakov DA, Jensen TP, Tyurikova O.
europepmc   +1 more source

Production and Formulation of Alcanivorax borkumensis SK2 Cell Powders for Marine Oil Spill Bioremediation

Biotechnology and Applied Biochemistry, EarlyView.
Abstract Oil spills pose severe threats to marine ecosystems and coastal communities. Alcanivorax borkumensis SK2, a marine bacterium with superior hydrocarbon‐degrading capabilities, emerges as a promising agent for bioremediation. This study identified an economical growth substrate for A.
Élisabeth Perreault, Denis Groleau, Patrick Vermette   +2 more
wiley   +1 more source

Impairment of Group I Metabotropic Glutamate Receptors in the Dorsal Striatum of the R451C-Neuroligin 3 Mouse Model of Autism Spectrum Disorder. [PDF]

J Neurochem
Meringolo M, Montanari M, D'Antoni S, Martella G, El Atiallah I, Ponterio G, Tassone A, Reverte I, Caprioli D, Strimpakos G, Pieroni L, Catania MV, Bonsi P.   +12 more
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

From trauma to depression: structural, synaptic, epigenetic, and molecular pathways linking early stress to lifelong vulnerability. [PDF]

Front Psychiatry
Takahashi M, Shelton RC.
europepmc   +1 more source

Multifunctional H2S‐activated metal‐organic framework systems for targeted colorectal cancer imaging and synergistic copper‐induced tumor regression

BMEMat, EarlyView.
The in situ reaction of Cu‐MOFs with endogenous H2S enabled PA imaging and facilitated combined PTT/chemotherapy for colorectal cancer therapy. Abstract Stimuli‐responsive nanomaterials offer significant potential for enhancing diagnostic accuracy, optimizing therapeutic efficacy, and advancing precision theranostics.
Nannan Zheng, Qinghui Wang, Zhiyue Cao, Chao Yu, Renkai Zhang, Kaiyan Xiang, Haoguang Wu, Kai Li, Qianqian Ni, Qiuyue Ma, Jing Mu, Xiaoyuan Chen, Liangcan He, Shaoqin Liu   +13 more
wiley   +1 more source