Results 251 to 260 of about 2,659,590 (353)

SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling. [PDF]

Acta Physiol (Oxf)
Staehr C, Login H, Melnikova EV, Bakun M, Ziemlinska E, Kisiswa L, Ardestani SB, Nolte SS, Beck HC, Hansen LMB, Postnov D, Verkhratsky A, Malik AR, Nykjaer A, Matchkov VV.   +14 more
europepmc   +1 more source

Metal‐Mediated Protein Engineering within Live Cells

Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.
This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

Glutamate promotes CCL2 expression to recruit tumor-associated macrophages by restraining EZH2-mediated histone methylation in hepatocellular carcinoma. [PDF]

Oncoimmunology
Chen J, Sun HW, Wang RZ, Zhang YF, Li WJ, Wang YK, Wang H, Jia MM, Xu QX, Zhuang H, Xue N.   +10 more
europepmc   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Immunoexcitoxicity as the possible major pathophysiology behind multiple sclerosis and other autoimmune disorders. [PDF]

Surg Neurol Int
Blaylock RL.
europepmc   +1 more source

Physics of Protein Aggregation in Normal and Accelerated Brain Aging

BioEssays, EarlyView.
Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay, Andrea Sturchio, Alberto Imarisio, Emily J. Hill, Brady Williamson, Kora Montemagno, Christian Hoffmann, Hugo Le Roy, Dragomir Milovanovic, Fredric P. Manfredsson   +9 more
wiley   +1 more source

A Window to the Brain-The Enduring Impact of Vision Research. [PDF]

Brain Sci
Ayoub G.
europepmc   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source