Results 281 to 290 of about 301,762 (292)
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2000
Publisher Summary Glutamate receptors come in two types: ionotropic and metabotropic. The ionotropic receptors are ligand-gated ion channels. Traditionally, ionotropic glutamate receptors have been classified according to their preferred agonists into: AMPA (a-amino-3- hydroxy-5-methyl-4-isoxazoleproprionate), kainate and NMDA (N-methyl- D-aspartate ...
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Publisher Summary Glutamate receptors come in two types: ionotropic and metabotropic. The ionotropic receptors are ligand-gated ion channels. Traditionally, ionotropic glutamate receptors have been classified according to their preferred agonists into: AMPA (a-amino-3- hydroxy-5-methyl-4-isoxazoleproprionate), kainate and NMDA (N-methyl- D-aspartate ...
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Glutamate Receptor Antagonists
Headache Currents, 2004GLUR5 Antagonists as Novel Migraine TherapiesBACKGROUND: L‐glutamate activates neurons in the trigeminal nucleus caudalis (TNC). Furthermore, non‐NMDA ionotropic glutamate receptors such as GluR5 are expressed in rat trigeminal ganglion (TG), and GluR5 receptors play an important role in central sensitization (CS).
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Chapter 24 Glutamate receptors in epilepsy
1998Glutamatergic synapses play a critical role in all epileptic phenomena. Broadly enhanced activation of post-synaptic glutamate receptors (ionotropic and metabotropic) is proconvulsant. Antagonists of NMDA receptors and AMPA receptors are powerful anticonvulsants in many animal models of epilepsy.
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Metabotropic glutamate receptors
Pharmacology Biochemistry and Behavior, 2002openaire +3 more sources
2000
During the past decade, pharmacological, electrophysiological, and molecular biological studies have yielded a detailed, albeit imperfect picture of the assembly and operation of NMDA receptors in the central nervous system. While a review of all aspects of NMDA receptor biology is clearly beyond the scope of this chapter, it is important to review ...
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During the past decade, pharmacological, electrophysiological, and molecular biological studies have yielded a detailed, albeit imperfect picture of the assembly and operation of NMDA receptors in the central nervous system. While a review of all aspects of NMDA receptor biology is clearly beyond the scope of this chapter, it is important to review ...
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The Glutamate Receptor Ion Channels
Pharmacological Reviews, 1999Dingledine, R +3 more
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MOLECULAR BIOLOGY OF THE GLUTAMATE RECEPTORS
Clinical Neuropharmacology, 1992Boulter, J. +9 more
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