Results 61 to 70 of about 183,883 (256)

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

The contrast effect of blocker of AMPA/KA glutamatereceptors IEM 1751 on stimulated gastric acid secretionby pentagastrin and histamine in rats

Current Issues in Pharmacy and Medical Sciences, 2009
In acute experiments on 71 white rats by the method of isolated stomach perfusion by Ghosh and Schild it was established that in rats with an intact nervous system antagonist of central and peripheral AMPA/KA glutamate receptors IEM 1751 did not ...
Tetyana Falalyeyeva, Tetyana Beregova, Vitaliy Kukharskyy   +2 more
doaj  

Glutamate Receptor Signaling in Retina Müller Cells: Plausible Role in Neurodegeneration

Receptors
The retinal network relies on glutamate, the primary excitatory neurotransmitter involved in the visual cycle. Glutamate transactions are carried out by an array of distinct receptors and transporters distributed across both pre- and post-synaptic ...
Bolaji Oyetayo, Yurixy Mendoza-Silva, Temitayo Subair, Luisa C Hernández-Kelly, Marie-Paule Felder-Schmittbuhl, Tatiana N. Olivares-Bañuelos, Arturo Ortega   +6 more
doaj   +1 more source

The Hippocampus Is the Place to Be: Opioid Receptors and LTP

Cell Reports, 2019
Nam et al. (2019) genetically modulate the expression of astrocytic μ-opioid receptors to reveal they are necessary for drug-induced conditioned place preference.
Thomas M. Sanderson, John Georgiou, Patrick Tidball, Graham L. Collingridge   +3 more
doaj   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex

Neurobiology of Disease, 2007
In addition to the loss of spinal motor neurons, amyotrophic lateral sclerosis (ALS) is also associated with degeneration of corticospinal layer V pyramidal neurons and decreased glutamate transport in the cortex. We characterized the glutamate receptors
Kate C. Young, Daniel S. McGehee, James R. Brorson   +2 more
doaj   +1 more source

Alterations of Astrocytes in the Context of Schizophrenic Dementia

Frontiers in Pharmacology, 2020
The levels of the astrocyte markers (GFAP, S100B) were increased unevenly in patients with schizophrenia. Reactive astrogliosis was found in approximately 70% of patients with schizophrenia.
Vadim V. Tarasov, Andrey A. Svistunov, Vladimir N. Chubarev, Susanna S. Sologova, Polina Mukhortova, Dmitrii Levushkin, Siva G. Somasundaram, Cecil E. Kirkland, Sergey O. Bachurin, Gjumrakch Aliev, Gjumrakch Aliev, Gjumrakch Aliev, Gjumrakch Aliev   +12 more
doaj   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Mechanisms of glutamate metabolic function and dysfunction in vascular dementia

Neuroprotection
As the global population ages, research on the pathogenesis and treatment options for older patients with dementia has become increasingly important.
Jiawen Wang, Yingmei Zhang, Ning Tian, Dongshan Ya, Jiaxin Yang, Yanlin Jiang, Xiaoxia Li, Xiaohui Lin, Bin Yang, Qinghua Li, Rujia Liao   +10 more
doaj   +1 more source

CRF1/CRF2 and MC3/MC4 Receptors Affect Glutamate- Induced Food Intake in Neonatal Meat-Type Chicken

Brazilian Journal of Poultry Science, 2019
Central glutamate, melanocortin and corticotropin systems have mediatory role on several physiologic functions in the brain, but their interactions on appetite regulation are not fully elicited.
F Ahmadi, M Zendehdel, V Babapour, N Panahi   +3 more
doaj   +1 more source