Results 261 to 270 of about 1,315,748 (336)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Angiogenesis in Glioblastoma-Treatment Approaches. [PDF]

Cells
Nowacka A, Śniegocki M, Smuczyński W, Bożiłow D, Ziółkowska E.   +4 more
europepmc   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Sunitinib induced glomerular thrombotic microangiopathy in a patient with refractory pancreatic neuroendocrine tumour. [PDF]

J Clin Pathol
Khan A, Consing Gangelhoff M, Moubarak S, Herrmann S, Nooruddin K, Alexander M.   +5 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Microglia efferocytosis: an emerging mechanism for the resolution of neuroinflammation in Alzheimer's disease. [PDF]

J Neuroinflammation
Chen Y, Kou Y, Ni Y, Yang H, Xu C, Fan H, Liu H.   +6 more
europepmc   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Neutrophils in Tissue Injury and Repair: Molecular Mechanisms and Therapeutic Targets. [PDF]

MedComm (2020)
Yang L, Shi F, Cao F, Wang L, She J, He B, Xu X, Kong L, Cai B.   +8 more
europepmc   +1 more source

The Use of Neurons Derived from Pluripotent Stem Cells to Study Nerve-Cancer Cell Interactions. [PDF]

Int J Mol Sci
Jiménez A, López-Ornelas A, Gutiérrez-de la Cruz N, Puente-Rivera J, Mayen-Quinto RD, Sánchez-Monciváis A, Ignacio-Mejía I, Albores-Méndez EM, Vargas-Hernández MA, Estudillo E.   +9 more
europepmc   +1 more source