Di-san junyi daxue xuebao, 2019 Objective To investigate the changes in the expression of fibroblast growth factor receptors 1-3 (FGFR1-3) at different stages of osteogenic differentiation and clarify the role of FGFR signaling in osteogenic differentiation.
MO Qifei, YANG Peng, SU Nan, CHEN Lin
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Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer. [PDF]
PLoS ONE, 2013 INTRODUCTION: Male breast cancer accounts for 0.5-1% of all breast cancers and is generally diagnosed at higher stage than female breast cancers and therefore might benefit from earlier detection and targeted therapy.
Jeroen F Vermeulen +4 more
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Fibroblast Growth Factor Receptors (FGFRs) and Noncanonical Partners in Cancer Signaling
Cells, 2021 Increasing evidence indicates that success of targeted therapies in the treatment of cancer is context-dependent and is influenced by a complex crosstalk between signaling pathways and between cell types in the tumor.
Harriet R. Ferguson +2 more
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Expression of transforming growth factor-beta isoforms and their receptors in chronic tendinosis [PDF]
, 2001 Chronic tendon lesions are degenerative conditions and may represent a failure to repair or remodel the extracellular matrix after repeated micro-injury.
Curry, V +5 more
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H3 histamine receptor-mediated activation of protein kinase calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo [PDF]
, 2009 Histamine regulates functions via four receptors (HRH1, HRH2, HRH3, and HRH4). The D-myo-inositol 1,4,5-trisphosphate (IP(3))/Ca(2+)/protein kinase C (PKC)/mitogen-activated protein kinase pathway regulates cholangiocarcinoma growth.
A. Vetuschi +13 more
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Effects of growth factors and receptor blockade on gastrointestinal cancer [PDF]
, 2004 The advent of recombinant peptide technology offers the potential to use one or several peptides to treat a variety of gastrointestinal conditions. However, although cell culture and animal models have shown proof of concept, we are still at a relatively
Ghosh, S, Playford, RJ, Wassan, H
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Animals, 2021 The oviduct presents the ideal conditions for fertilization and early embryonic development. In this study, (i) vascularization pattern; (ii) microvascular density; (iii) transcripts of angiogenic factors (FGF1, FGF2, VEGF) and their receptors—FGFR1 ...
Pedro Pinto-Bravo +10 more
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Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
, 2015 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
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The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]
, 2014 G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin +8 more
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BRET biosensor analysis of receptor tyrosine kinase functionality
Frontiers in Endocrinology, 2013 Bioluminescence resonance energy transfer (BRET) is an improved version of earlier resonance energy transfer technologies used for the analysis of biomolecular protein interaction.
Sana eSiddiqui +4 more
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