Results 291 to 300 of about 1,315,748 (336)
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1988
Growth factors and growth factor receptors may be involved in the abnormal growth characteristic of cancer, and both entities are encoded by known proto-oncogenes. Growth factors may act as self-stimulants (autocrine control stimulants of nearby cells(paracrine control), or stimulants of distant tissue (hormonal control).
Edison T. Liu +2 more
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Growth factors and growth factor receptors may be involved in the abnormal growth characteristic of cancer, and both entities are encoded by known proto-oncogenes. Growth factors may act as self-stimulants (autocrine control stimulants of nearby cells(paracrine control), or stimulants of distant tissue (hormonal control).
Edison T. Liu +2 more
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Growth Factors, Growth-Factor Receptors and Oncogenes
Bio/Technology, 1985In this review we summarize the current knowledge of polypeptide growth factors, their receptors and oncogenes. Recent studies indicate that oncogenes are linked to growth factors and to growth factor receptors, suggesting that these molecules participate in the proliferation of normal and neoplastic cells.
A. Avivi +3 more
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1991
Proliferation of normal cells is regulated through the complex interaction of each cell with neighboring homologous and heterologous cells and extracellular tissue components forming its microenvironment. In addition to the cell-cell and cell-extracellular matrix contact, the proliferation of cells is regulated by a variety of soluble growth factors ...
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Proliferation of normal cells is regulated through the complex interaction of each cell with neighboring homologous and heterologous cells and extracellular tissue components forming its microenvironment. In addition to the cell-cell and cell-extracellular matrix contact, the proliferation of cells is regulated by a variety of soluble growth factors ...
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International Journal of Neuroscience, 1985
Nerve growth factor is a polypeptide hormone that is required for the normal growth and development of the embryonic sensory and sympathetic nervous systems. On these cells, there are two different receptors for the nerve growth factor. Recently, these receptors have been isolated from three cell types and shown to have essentially the same binding ...
David J. Ennulat +3 more
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Nerve growth factor is a polypeptide hormone that is required for the normal growth and development of the embryonic sensory and sympathetic nervous systems. On these cells, there are two different receptors for the nerve growth factor. Recently, these receptors have been isolated from three cell types and shown to have essentially the same binding ...
David J. Ennulat +3 more
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Growth factor and growth factor receptor in radiation carcinogenesis
Radiation and Environmental Biophysics, 1991link_to_subscribed_fulltext
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The epidermal growth factor receptor family [PDF]
Endocrine-Related Cancer, 2005 The epidermal growth factor receptor family consists of four receptor genes and at least 11 ligands, several of which are produced in different protein forms. They create an interacting system that has the ability to receive and process information that results in multiple outputs.
L.A. Bazley, William J. Gullick
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Growth factors, their receptors and development
American Journal of Medical Genetics, 1989AbstractThe hypothesis is put forward that the localized production of growth factors and the regulation both of their receptors and their receptor‐triggered transmembrane signaling reactions played an important role in organ development. The developing palate is used as an example to support this hypothesis.
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Growth factor receptors and medulloblastoma
Journal of Neuro-Oncology, 1996Growth factors and their receptors play important roles in the regulation of cell division, development and differentiation. Neurotrophins are growth factors which have not been shown, until recently, to be associated with human neoplasia. Medulloblastoma is a central nervous system tumor which is thought to arise from the external granule cell layer ...
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Growth factors, receptors and cancer
BioEssays, 1986AbstractIt now appears that the molecular events associated with the mitogenic action of growth factors are also the events perturbed in neoplastic lesions. This review outlines the relevance of our recent progress in the biochemistry of growth factors and their receptors to the induction and maintenance of the neoplastic state.
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Fibroblast Growth Factor Receptor Inhibitors
Current Pharmaceutical Design, 2012Fibroblast growth factor receptors (FGFRs) play an important role in embryonic development, angiogenesis, wound healing, cell proliferation and differentiation. The fibroblast growth factor receptor (FGFR) isoforms have been under intense scrutiny for effective anticancer drug candidates.
Raveendra Dayam +4 more
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