Results 241 to 250 of about 89,612 (317)

Updated insights into the molecular pathogenesis of canine atopic dermatitis

Veterinary Dermatology, EarlyView.
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley   +1 more source

Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson's Disease. [PDF]

Neurosci Bull
Xu HT, Xi XY, Zhou S, Xie YY, Cui ZS, Zhang BB, Xie ST, Li HZ, Zhang QP, Pan Y, Zhang XY, Zhu JN.   +11 more
europepmc   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

Veterinary Dermatology, EarlyView.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki, Santosh K. Mishra   +1 more
wiley   +1 more source

Involvement of Pruritus, Gut Dysbiosis and Histamine-Producing Bacteria in Paraneoplastic Syndromes. [PDF]

Biomedicines
Georgescu D, Lighezan D, Ionita M, Ciubotaru P, Cozma G, Faur A, Suceava I, Ancusa OE, Buzas R.   +8 more
europepmc   +1 more source

Oxyntomodulin physiology and its therapeutic development in obesity and associated complications

The Journal of Physiology, EarlyView.
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh, Ming Chuen Chong, Alexander D. Miras, Carel W. le Roux   +3 more
wiley   +1 more source

Comparing the effectiveness of four antihistamines with olopatadine in healthy Thoroughbred horses.

J Vet Med Sci
Ikeda Y, Kuroda T, Mita H, Tamura N, Ohta M.   +4 more
europepmc   +1 more source

Current insights and prospects for the pathogenesis and treatment of clinical manifestations associated with Down syndrome through neurotransmitter, inflammatory, and oxidative stress pathways. [PDF]

Front Pharmacol
Alasmari F, Ahmad A, Alsanea S, Hammad AM, Al-Qerem W.   +4 more
europepmc   +1 more source

Functional sympatholysis of neuropeptide Y‐mediated vasoconstriction in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Neuropeptide Y (NPY) is a neurotransmitter that elicits potent vasoconstriction and is co‐released with noradrenaline during sympathoexcitation, as occurs during exercise. We assessed whether NPY‐mediated vasoconstriction is blunted during exercise (i.e.
Denis J. Wakeham, Sarah L. Hissen, James P. MacNamara, Scott L. Davis, Paul J. Fadel, Benjamin D. Levine, Christopher M. Hearon Jr   +6 more
wiley   +1 more source

Allergen Immunotherapy: Pitfalls, Perks and Unexpected Allies. [PDF]

Int J Mol Sci
Tamaș TP, Ciurariu E.
europepmc   +1 more source

Mouse Adrenal Macrophages Are Associated with Pre- and Postsynaptic Neuronal Elements and Respond to Multiple Neuromodulators. [PDF]

eNeuro
Whim MD.
europepmc   +1 more source