Results 31 to 40 of about 89,612 (317)

Network adaptation improves temporal representation of naturalistic stimuli in drosophila eye: II Mechanisms [PDF]

, 2009
Retinal networks must adapt constantly to best present the ever changing visual world to the brain. Here we test the hypothesis that adaptation is a result of different mechanisms at several synaptic connections within the network.
A Borst, A Kolodziejczyk, A Nikolaev, AD Straw, AL Fairhall, AL Fairhall, Anton Nikolaev, B Wark, BG Burton, BG Burton, BN Lundstrom, Cahir J. O'Kane, CE Shannon, DG Stavenga, DJ Field, DW Dong, E Schneidman, E Warrant, EL Mah, Ernest Greene, F Attneave, G Buchsbaum, G Schwartz, GG de Polavieja, GG de Polavieja, GG de Polavieja, Gonzalo G. de Polavieja, GW Davis, H Alle, H Barlow, H Clague, HG Krapp, I Sinakevitch, IA Meinertzhagen, IA Meinertzhagen, J Rister, J Tanaka, JD Armitage, JH van Hateren, JH van Hateren, JH van Hateren, JH van Hateren, JH van Hateren, JH van Hateren, JJ Atick, JJ Atick, JL Puchalla, K Götz, K Kirschfeld, L Zheng, Lei Zheng, M Heisenberg, M Heisenberg, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Järvilehto, M Land, M Stemmler, M Weckstrom, Mikko Juusola, MV Srinivasan, N Brenner, N Uchida, O Faivre, O Sayeed, R Hummel, R Kern, R Linsker, R Segev, R Wolf, RC Hardie, RO Uusitalo, RR de Ruyter van Steveninck, RS Brinkworth, S Laughlin, S Tang, SA Baccus, SB Laughlin, SB Laughlin, SM Smirnakis, SN Fry, SN Fry, SR Shaw, ST Hong, T Gollisch, TM Cover, TO Sharpee, Trevor J. Wardill, V Wolfram, XJ Wang, Y Dan, Y Shu   +99 more
core   +5 more sources

Increased Sensitivity of Mice Lacking Extrasynaptic δ-Containing GABAA Receptors to Histamine Receptor 3 Antagonists

Frontiers in Pharmacology, 2020
Histamine/gamma-aminobutyric acid (GABA) neurons of posterior hypothalamus send wide projections to many brain areas and participate in stabilizing the wake state.
Shamsiiat Abdurakhmanova, Milo Grotell, Jenna Kauhanen, Anni-Maija Linden, Esa R. Korpi, Pertti Panula   +5 more
doaj   +1 more source

Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor

Journal of Innate Immunity, 2022
We found that histamine (10−9 M) did not have any effect on the in vitro capture of Escherichia coli by neutrophils but accelerated its intracellular killing.
Karim Dib, Amal El Banna, Clara Radulescu, Guillermo Lopez Campos, Gerard Sheehan, Kevin Kavanagh   +5 more
doaj   +1 more source

Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis. [PDF]

, 2017
Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
Firestein, Gary S, Kim, Bo-Mi, Kim, Hae-Rim, Kim, Kyoung-Woon, Lee, Kyung-Ann, Lee, Sang-Heon   +5 more
core   +1 more source

Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]

, 2004
Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Aarnisalo, Antti A., Karlstedt, Kaj, Lozada, Adrian F., Panula, Pertti, Stark, Holger   +4 more
core   +2 more sources

Structural basis of ligand recognition and activation of the histamine receptor family. [PDF]

Nat Commun
Histamine is a biogenic amine that is critical in various physiological and pathophysiological processes, including but not limited to allergic reactions, wakefulness, gastric acid secretion and neurotransmission.
Zhang X, Liu G, Zhong YN, Zhang R, Yang CC, Niu C, Pu X, Sun J, Zhang T, Yang L, Zhang C, Li X, Shen X, Xiao P, Sun JP, Gong W.   +15 more
europepmc   +2 more sources

Direct imaging of lateral movements of AMPA receptors inside synapses [PDF]

EMBO J 22, 18 (15/09/2003) 4656-65, 2007
Trafficking of AMPA receptors in and out of synapses is crucial for synaptic plasticity. Previous studies have focused on the role of endo/exocytosis processes or that of lateral diffusion of extra-synaptic receptors. We have now directly imaged AMPAR movements inside and outside synapses of live neurons using single-molecule fluorescence microscopy ...
arxiv   +1 more source

Differential expression of histamine receptors in the bladder wall tissues of patients with bladder pain syndrome/interstitial cystitis – significance in the responsiveness to antihistamine treatment and disease symptoms

BMC Urology, 2019
Background Activation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity of the bladder. The present study
Hui Shan, Er-Wei Zhang, Peng Zhang, Xiao-Dong Zhang, Ning Zhang, Peng Du, Yong Yang   +6 more
doaj   +1 more source

H3 histamine receptor-mediated activation of protein kinase calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo [PDF]

, 2009
Histamine regulates functions via four receptors (HRH1, HRH2, HRH3, and HRH4). The D-myo-inositol 1,4,5-trisphosphate (IP(3))/Ca(2+)/protein kinase C (PKC)/mitogen-activated protein kinase pathway regulates cholangiocarcinoma growth.
A. Vetuschi, F. Y. Meng, FRANCHITTO, Antonio, G. Alpini, G. Carpino, GAUDIO, EUGENIO, H. Francis, J. Venter, M. White, MANCINELLI, ROMINA, ONORI, PAOLO, R. Sferra, S. Demorrow, S. Kopriva   +13 more
core   +1 more source

Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]

, 2018
Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
core   +2 more sources