Results 111 to 120 of about 12,014 (244)

Localisation of mRNAs for diamine oxidase and histamine receptors H1 and H2, at the feto-maternal interface of human pregnancy.

, 2001
OBJECTIVE AND DESIGN\ud \ud To localise mRNAs for the histamine receptors H1, H2 and H3, and for diamine oxidase, in the placenta and decidua of the human feto-maternal interface.\ud \ud MATERIALS AND METHODS\ud \ud Complementary DNA for each mRNA of ...
Sullivan, Mark, Sullivan, Mark H.F., Brew, Obed   +2 more
core   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal, Roshanay Ejaz Awan, Hur Abbas, Zahra Sania, Ashna Habib, Syeda Kaneez Sakina, Amina Mahmud, Mohammed Mahmmoud Fadelallah Eljack   +7 more
wiley   +1 more source

Genome Mining Approaches for Toxicant Discovery: A Case Study Examining Receptor Proteins for Pest Management in New Zealand

New Zealand Journal of Zoology, Volume 53, Issue 2, June 2026.
Pest control is a global challenge for agriculture and biodiversity conservation, with the use of existing vertebrate pesticides increasingly constrained by regulatory, environmental, and social pressures. There is an urgent need for safer and more species‐selective toxicants, but the development of novel vertebrate pesticides remains technically ...
Erica R. Hendrikse, Natalie J. Forsdick, Wanting Jiao, Brian Hopkins   +3 more
wiley   +1 more source

Functional characterisation of the novel histamine H(3) receptor agonist, VUF 5810, on the guinea-pig isolated ileum

, 2003
It is known that the activation of prejunctionally-located histamine H3 receptors down-regulates the exocytotic acetylcholine release from the myenteric plexus and thus produces a negative control on the intestinal motility [1].
POZZOLI, Cristina, MENOZZI, Alessandro, KITBUNNADAJ R., TIMMERMANN H., LEURS R., TIMMERMAN H., POLI, Enzo, CORUZZI G.   +7 more
core   +1 more source

Comparative Sleep Architecture Profiles of Antidepressants in Mice: Pharmacological Characterization of Paroxetine, Sertraline, Duloxetine, Mirtazapine and Vortioxetine

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study compared five antidepressants (paroxetine, sertraline, duloxetine, mirtazapine, and vortioxetine) in mice using EEG/EMG, revealing distinct effects on REM and NREM sleep. The figure illustrates changes in sleep architecture during the light phase (ZT0–12).
Junya Maruoka, Ryo Egami, Yuto Akita, Kohei Kozuka, Yusuke Kakumoto, Tetsuro Kikuchi, Kazuhiko Kume   +6 more
wiley   +1 more source

Interaction of Local Anaesthetics with Histamine H1 Receptors in Guinea-pig Ileum

, 1997
The interaction of amine local anaesthetics and related compounds with histamine H1 receptors was investigated in guinea-pig ileal longitudinal muscle.
Shuhei Horio, Toshitaka Nagare, Hideki Moritoki, Yukio Ishida   +3 more
core   +1 more source

Species differences in histamine receptors in the seminal vesicle

, 1981
Histamine and specific H1- and H2-receptor agonists and antagonists in conjunction with phentolamine and (or) reserpine pretreatment were used to characterize histamine receptor(s) in the seminal vesicle of rat and guinea pig.
M. M. Vohra, C. M. MacIntosh
core   +1 more source

Binding characteristics of cetirizine and levocetirizine to human H1 histamine receptors: Contribution of Lys191 and Thr194

, 2002
Competition experiments with [3H]mepyramine showed that cetirizine and its enantiomers, levocetirizine and (S)-cetirizine, bound with high affinity and stereoselectivity to human H1 histamine receptors (Ki values of 6, 3, and 100 nM, respectively ...
Massingham, R, Chatelain, P, Gillard, M, Gillard, Michel, Chatelain, Pierre, Moguilevsky, Nicole, Massingham, Roy, Van Der Perren, Christy, Van der Perren, C   +8 more
core   +1 more source

The Effects of Histaminergic Agents in the Nucleus Accumbens of Rats in the Elevated Plus-Maze Test of Anxiety

Basic and Clinical Neuroscience, 2010
Introduction/Aims: The nucleus accumbens (NAc) receives histaminergic neurons from tuberomammillary nuclei. There are also reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Mohammad-Reza Zarrindast, Saba Taherid, Ameneh Rezayof   +2 more
doaj  

Role of histamine H1- and H2-receptors in myoelectric activity of small bowel in the dog

, 1980
Studies were conducted in conscious dogs implanted with monopolar silver electrodes along the small intestine to determine whether the intestinal motility response to histamine is mediated by H1-receptors alone or whether H2-receptors are also involved ...
R. Siebers, S. J. Konturek
core   +1 more source