Results 101 to 110 of about 12,014 (244)
Journal of Pharmacy & Pharmaceutical Sciences, 2019 Purpose: Fexofenadine (FXF) is the active metabolite of terfenadine with selective peripheral H1 receptor antagonist activity. FXF is a third-generation antihistamine, non-sedating, rapid and very long acting used in symptoms associated with allergic ...
Natalia Kordulewska +4 more
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren +8 more
wiley +1 more source
, 2009 Active traumatic brain injury (TBI), high levels of histamine may participate in the pathophysiology of secondary brain injury. Histaminergic neurons project throughout the entire brain and are activate during brain diseases accompanied by edema ...
RIGO, Jean-Michel +4 more
core +1 more source
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties
Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.ABSTRACT Respiratory disorders, ranging from acute viral infections such as influenza and bronchitis to chronic inflammatory conditions including chronic obstructive pulmonary disease, asthma, emphysema, and pneumonia, represent a major global health burden, affecting millions annually. Traditional Anatolian folk medicine has long relied on plant‐based
Golshan Zare +5 more
wiley +1 more source
Mediators of Inflammation, 1995 The presence of histamine H3 receptors was evaluated on the rat aorta endothelium. In the presence of pyrilamine (1 nM, 7 nM, 10 nM) or thioperamide (1 nM, 10 nM, 30 nM) the concentration–response curve for histamine-induced (0.1 nM − 0.01 mM ...
D. M. Djuric, I. Z. Andjelkovic
doaj +1 more source
Focus on the cetirizine use in clinical practice: a reappraisal 30 years later
Multidisciplinary Respiratory Medicine, 2019 Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma ...
Angelo G. Corsico +7 more
doaj +1 more source
Severe Hair Dye Anaphylaxis Caused by Toluene‐2,5‐ Diamine Identified by Positive in Vitro Tests
Contact Dermatitis, EarlyView.
Eglė Janušonytė +3 more
wiley +1 more source
Neuroprotective Effects of Phenothiazines on Acute Ischemic Stroke
CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.For acute ischemic stroke due to large vessel occlusion, adjunctive neuroprotective therapy with mechanical thrombectomy is important; however, current treatment options are relatively limited. Phenothiazines such as chlorpromazine and promethazine (C + P) have shown potential neuroprotective effects in preclinical studies.
Qi Wang +4 more
wiley +1 more source