Results 41 to 50 of about 21,097 (244)

Histamine H1-receptors modulate somatostatin receptors coupled to the inhibition of adenylyl cyclase in the rat frontoparietal cortex [PDF]

, 1997
Since exogenous histamine has been previously shown to increase the somatostatin (SS) receptor-effector system in the rat frontoparietal cortex and both histamine H1-receptor agonists and SS modulate higher nervous activity and have anticonvulsive ...
Arilla Ferreiro, Eduardo, Ocaña Fuentes, Aurelio, Puebla Jiménez, Lilian   +2 more
core   +3 more sources

Antihistamines for the treatment of urticaria in Mexico

Revista Alergia México, 2015
There are four types of histamine receptors. Allergic symptoms, especially those in rhinoconjunctivitis and urticaria, are mainly caused by activation of histamine receptor 1 (H1).
Désirée Larenas-Linnemann, Mario Sánchez-Borges, Blanca Estela Del Río-Navarro, María de Lourdes Alonzo-Romero Pareyón, César Alfonso Maldonado-García, Enrique Mendoza-López, José Antonio Ortega-Martell, Juan José Luis Sienra-Monge, Miguel Alejandro Medina-Ávalos, María Isabel Rojo-Gutiérrez, Angélica María Beirana-Palencia, Jorge Bernardo Vargas-Correa, Carlos Báez-Loyola, Ruth Ivonne Mireya Ramírez-Segura, María Graciela Guzmán-Perea   +14 more
doaj   +1 more source

Antihistaminic, Anti-Inflammatory, and Antiallergic Properties of the Nonsedating Second-Generation Antihistamine Desloratadine: a Review of the Evidence

World Allergy Organization Journal, 2011
The allergy cascade presents widespread inflammatory and proinflammatory activation, robust cytokine and chemokine signaling, and heterogeneous immune and endothelial responses that lead ultimately to the manifestations of allergic reaction. Histamine, a
G. Walter Canonica, MD, Michael Blaiss, MD   +1 more
doaj   +1 more source

Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo [PDF]

, 2012
Objective: Betahistine is a histamine H1-receptor agonist and H3-receptor antagonist that is administered to treat Menière’s disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the
Bertlich, Mattis, Canis, Martin, Ihler, Fritz, Sharaf, Kariem, Strieth, Sebastian, Strupp, Michael   +5 more
core   +3 more sources

Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype

Journal of Pharmacological Sciences, 2004
Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi, Nozomi Kawakami, Yousuke Wakayama, Norimasa Izumi, Shuhei Horio, Hiroyuki Fukui   +5 more
doaj   +1 more source

Stimulation of Histamine H1 Receptor Up-Regulates Histamine H1 Receptor Itself Through Activation of Receptor Gene Transcription

Journal of Pharmacological Sciences, 2007
Histamine is a major mediator in allergy acting mainly through the histamine H(1) receptor (H1R). Although H1R up-regulation has been suggested as an important step for induction of allergic symptoms, little is known about the regulation of H1R level. Here we report that the activation of H1R up-regulates H1R through augmentation of H1R mRNA expression
Asish K. Das, Sachiho Yoshimura, Ryoko Mishima, Katsumi Fujimoto, Hiroyuki Mizuguchi, Shrabanti Dev, Yousuke Wakayama, Yoshiaki Kitamura, Shuhei Horio, Noriaki Takeda, Hiroyuki Fukui   +10 more
openaire   +4 more sources

Participation of Histamine H3 Receptors in Experimental Allergic Rhinitis of Mice

Journal of Pharmacological Sciences, 2008
The present study was performed to study the participation of histamine H3 receptors in nasal symptoms using Sch 50971, a potent and selective agonist of the H3 receptor.
Emiko Yokota, Shoji Kuyama, Yukio Sugimoto, Masami Ogawa, Chiaki Kamei   +4 more
doaj   +1 more source

Intestinal epithelial responses to Salmonella enterica serovar Enteritidis: Effects on intestinal permeability and ion transport [PDF]

, 2019
Salmonella infection of chickens that leads to potential human foodborne salmonellosis continues to be a major concern. Chickens serve as carriers but, in contrast to humans, rarely show any clinical signs including diarrhea.
Aschenbach, J. R., Awad, W. A., Hess, C., Hess, M., Khayal, B.   +4 more
core   +1 more source

Histamine H1‐receptor‐mediated modulation of NMDA receptors signaling responses

Pharmacology Research & Perspectives
This study attempted to clarify the role of histamine H1 receptors in epilepsy by exploring the effects of agonists and inverse agonists on the rundown of the current induced by iterative applications of NMDA or GABA in primary neuronal culture ...
J.‐M. Arrang, V. Armand
doaj   +1 more source

Ameliorative Effect of a Hippocampal Metabotropic Glutamate– Receptor Agonist on Histamine H1 Receptor Antagonist–Induced Memory Deficit in Rats

Journal of Pharmacological Sciences, 2010
This study was performed to investigate the ameliorative effects of metabotropic glutamate (mGlu)-receptor agonists on histamine H1 receptor antagonist–induced spatial memory deficit and the decrease in hippocampal theta activity in rats. Intraperitoneal
Takayoshi Masuoka, Azusa Mikami, Chiaki Kamei   +2 more
doaj   +1 more source