Results 91 to 100 of about 784,733 (223)

The Effects of Histaminergic Agents in the Nucleus ccumbens of Rats in the Elevated Plus-Maze Test of Anxiety [PDF]

open access: yesIranian Journal of Psychiatry, 2010
"n Objective: "n The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Ameneh Rezayof   +2 more
doaj  

H3 antagonists and postoperative cognitive dysfunction

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2019
Since histamine (HA) was first synthesized in 1907 and isolated as a bacterial contaminant of an extract of ergot in 1910, its role in health and disease and its molecular mechanism of action have been unraveled, leading to the formulation of an array of
Chandrasekhar Krishnamurti
doaj   +1 more source

Development of novel ligands influencing neurotransmission in the central nervous system [PDF]

open access: yes, 2007
The development of novel drugs targeting GPCRs is of particular interest since modulation of subfamilies of this receptor class highly influences neurotransmission in the central nervous system.
Sasse, Britta Caroline
core  

Histamine H1 Receptors in Neural Stem Cells Are Required for the Promotion of Neurogenesis Conferred by H3 Receptor Antagonism following Traumatic Brain Injury

open access: yesStem Cell Reports, 2019
Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao   +11 more
doaj   +1 more source

Opposite functions of histamine H1 and H2 receptors and H3 receptor in substantia nigra pars reticulata

open access: yes, 2006
The substantia nigra pars reticulata (SNr) is a key basal ganglia output nucleus. Inhibitory outputs from SNr are encoded in spike frequency and pattern of the inhibitory SNr projection neurons.
LeDoux, Mark S.   +4 more
core   +1 more source

Antinociceptive mechanisms of Bunium persicum essential oil in the mouse writhing test: role of opioidergic and histaminergic systems

open access: yesVeterinární Medicína, 2015
Bunium persicum (Boiss.) is an economically important medicinal plant growing wildly in arid regions in Iran. The fruit of B. persicum is widely used in traditional Iranian medicine to control colic pain and dysmenorrhoea.
M. Zendehdel, Z. Torabi, S. Hassanpour
doaj   +1 more source

Allergic Rhinoconjunctivitis: the Role of Histamine

open access: yesMediators of Inflammation, 1994
Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
doaj   +1 more source

Histamine Regulates Molecular Clock Oscillations in Human Retinal Pigment Epithelial Cells via H1 Receptors

open access: yesFrontiers in Endocrinology, 2018
Vertebrate eyes are known to contain circadian clocks, but their regulatory mechanisms remain largely unknown. To address this, we used a cell line from human retinal pigment epithelium (hRPE-YC) with stable coexpression of reporters for molecular clock ...
Eri Morioka   +4 more
doaj   +1 more source

Histamine H1- and H2-receptor vasodilation of canine intestinal circulation.

open access: yes, 1977
Studies were conducted in anesthetized dogs to determine whether the mesenteric vasodilator response to histamine is mediated by H1 receptors alone or whether H2 receptors are also involved in the response.
B L Tepperman   +4 more
core   +1 more source

Molecular basis for the interaction of histamine with the histamine H2 receptor.

open access: yesJournal of Biological Chemistry, 1992
We undertook these studies to characterize the molecular basis of the interaction of histamine with the H2 receptor. Key areas of homology in the structures of the histamine H2 and beta 2 adrenergic receptor suggested specific transmembrane amino acids that might be important for binding of histamine.
I, Gantz   +7 more
openaire   +2 more sources

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