Results 91 to 100 of about 19,126 (227)

Molecular Markers Distinguishing Early‐Stage Mycosis Fungoides From Atopic Dermatitis Skin Lesions

Experimental Dermatology, Volume 35, Issue 4, April 2026.
ABSTRACT Mycosis fungoides (MF) is the most common type of primary cutaneous T‐cell lymphoma, a disease characterized by malignant T cells that home to the skin. In early stages, clinical presentation is often indistinguishable from benign chronic inflammatory skin diseases such as atopic dermatitis (AD), posing a challenge for proper diagnosis and ...
Brandon D. Ng, Conor Whelan, Natalia Alkon, Agata Kurowski, Constanze Jonak, Patrick M. Brunner   +5 more
wiley   +1 more source

Histamine and its Effects Mediated via H3 Receptor – Potential Clinical Applications of H3 Antagonists

Acta Medica Martiniana, 2013
Histamine is one of the most important biogenic amines and it mediates numbers of physiological processes. It is also involved in majority of inflammatory diseases via its receptors H1, H2, H3 and H4.
Hanuskova E., Plevkova J.
doaj   +1 more source

The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons [PDF]

, 2012
Background Compound 48/80 is widely used in animal and tissue models as a “selective” mast cell activator. With this study we demonstrate that compound 48/80 also directly activates enteric neurons and visceral afferents.
A Eglezos, AM Gilfillan, AM Rothschild, Christopher Eastwood, D Levy, David Grundy, E Breunig, EM Kugler, Eva Maria Kugler, F De Jonge, G Barbara, G Chiang, G Katayama, J Giebel, J Janiszewski, Jemma Donovan, JK Law, K Michel, K Takeuchi, LJ Janssen, M Djaldetti, M Mousli, Michael Schemann, N Quinson, P Kovacs, P Kubes, R Kaur, S Buhner, SA Malin, Sabine Buhner, SC Bischoff, SW Kashem, TC Theoharides, TJ Heppner, TW Lovenberg, VA Palomaki, W Jiang, WD Paton, Wen Jiang, WG Paterson, Yvette Tache, Z Koszegi   +41 more
core   +2 more sources

Effects of prior heavy exercise on deoxygenation in deep versus superficial muscle regions during subsequent heavy exercise in adult males

Physiological Reports, Volume 14, Issue 7, April 2026.
Graphical summary of the effect of priming exercise on superficial vs. deep muscle deoxygenation. Abstract We assessed the effects of prior heavy‐intensity‐exercise (PHE) on microvascular deoxygenation in deep vastus lateralis muscle (VLd) compared with the superficial VL (VLs).
Weerapong Chidnok, Dai Okushima, Richie P. Goulding, David C. Poole, Thomas J. Barstow, Andrew M. Jones, Pieter‐Jan Marent, Narihiko Kondo, Shunsaku Koga   +8 more
wiley   +1 more source

The Effects of Histaminergic Agents in the Nucleus ccumbens of Rats in the Elevated Plus-Maze Test of Anxiety [PDF]

Iranian Journal of Psychiatry, 2010
"n Objective: "n The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Ameneh Rezayof, Saba Taheri, Mohammad-Reza Zarrindast   +2 more
doaj  

H3 antagonists and postoperative cognitive dysfunction

Journal of Anaesthesiology Clinical Pharmacology, 2019
Since histamine (HA) was first synthesized in 1907 and isolated as a bacterial contaminant of an extract of ergot in 1910, its role in health and disease and its molecular mechanism of action have been unraveled, leading to the formulation of an array of
Chandrasekhar Krishnamurti
doaj   +1 more source

Peculiarities of influence of single intragastric administration of H2-histamine receptor blockers of the second (nisatidine) and third (famotidine) generation on acid-peptic and mucoid-electrolyte secretion of the stomach in patients with duodenal ulcer

Львівський клінічний вісник, 2019
Introduction. Antisecretory drugs are commonly used in the complex treatment of most diseases of the upper gastrointestinal tract. Today, proton pomp inhibitors (PPI) have a priority in the basic treatment for acid-dependent diseases of the ...
Pliatsko M.
doaj   +1 more source

Histamine H2 Receptors in Nasal Mucosa.

Practica Oto-Rhino-Laryngologica, 1994
Nasal mucous membrane is a pathogenic site of Type I allergy (nasal allergy), and a number of studies have suggested the involvement of histamine H1 receptors in this region.Histamine H2 receptors, which are considered to suppress the activity of many immunity-related cells have, however been studied insufficiently.In this study, the number of ...
Shigehiko SATOH, Hitoshi SHIMADA, Kohtaro BABA   +2 more
openaire   +2 more sources

Histamine H1 Receptors in Neural Stem Cells Are Required for the Promotion of Neurogenesis Conferred by H3 Receptor Antagonism following Traumatic Brain Injury

Stem Cell Reports, 2019
Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao, Youchao Chen, Li Cheng, Lishi Fan, Han Chen, Yushan Wan, Yi You, Yanrong Zheng, Lei Jiang, Zhong Chen, Xiangnan Zhang, Weiwei Hu   +11 more
doaj   +1 more source

Efficacy of cimetidin in the prevention of ulcer formation in the stomach during immobilization stress [PDF]

The effect of stress on the formation of ulcers in the mucous membrane of the stomach, the increase in cyclic adenosine monophosphate level in the gastric tissues, and parietal cell structure alteration.
Dorofeyev, G. I., Gavrovskaya, L. K., Ivashkin, V. T., Litovskiy, I. A.   +3 more
core   +1 more source