Results 141 to 150 of about 42,332 (197)

Current perspectives on topical antiallergics. [PDF]

Indian J Ophthalmol
Gokhale NS.
europepmc   +1 more source

Differential Expression of Histamine H₃ Receptor In Healthy, Preneoplastic, and Tumoral Pancreatic Tissue: A Pilot Study. [PDF]

J Histochem Cytochem
Speisky D, Nicoud MB, Iotti A, Formoso K, Lauretta P, García de Dávila MT, Medina VA.   +6 more
europepmc   +1 more source

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Histamine H2-receptors on single central neurones

Nature, 1975
THE detection of histamine H2-receptor antagonists1,2 has provided fresh impetus to the investigation of central effects of histamine3–7 and its possible role as a neurotransmitter3,8–10. In the hypothalamus of rat and cat microelectrophoretically applied histamine excites a large number of cells.
H. Haas, U. Bucher
semanticscholar   +3 more sources

Multiple signaling pathways of histamine H2 receptors.

Agents and actions. Supplements, 1991
Histamine H2 receptor (H2R) has been shown to be coupled to adenylate cyclase. However, we have previously demonstrated that H2R-specific stimulation also activated phospholipase C in human HL-60 promyelocytic leukemia cells (Mitsuhashi M. et al. J. Biol. Chem. 264:18356, 1989).
M. Mitsuhashi, Payan Dg
semanticscholar   +3 more sources

Histamine H2-receptor antagonists

Baillière's Clinical Gastroenterology, 1988
The first histamine H2-receptor antagonists were developed in the early 1970s, and they have a dominant role in today's management of peptic ulceration. The original regimens using either cimetidine or ranitidine attempted to control acidity across the 24 hours, but more 'modern' regimens use a large single dose of the H2-blocker in the evening, which ...
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Histamine H2-Receptor Antagonists

Nursing Clinics of North America, 1991
In summary, histamine initiates acid secretion by stimulating the H2 subtype histamine receptor on parietal cells. Cimetidine, rantidine, famotidine, and nizantidine are histamine H2-receptor antagonists that block this action of histamine, reducing gastric acid output and concentration under both basal and stimulated conditions.
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Histamine H2 Receptor Biased Signaling Methods

2017
Fil: Fernandez, Natalia Cristina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Farmacologicas. Universidad de Buenos Aires. Facultad de Farmacia y Bioquimica.
Fernandez, Natalia Cristina, Shayo, Carina Claudia, Davio, Carlos Alberto, Monczor, Federico   +3 more
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Histamine H2-receptor antagonists.

Advances in internal medicine, 1978
Development of histamine H2-receptor antagonists has enhanced the understanding of histamine physiology and pharmacology. The effect of H2-receptor antagonists on gastrointestinal physiology has been studied extensively. These compounds inhibit gastric acid secretion in response to all known secretagogues and, in contrast to anticholinergic drugs ...
M, Feldman, C T, Richardson
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Potential histamine H2-receptor antagonists. 3. Methylhistamines

Journal of Medicinal Chemistry, 1976
Syntheses are described for all the mono- and some di- and trimethylhistamines. New methods are given for the known Npi, Ntau-, Nalpha-, 2-, and 4-methylhistamines and for the novel compounds, beta-methyl-, 4,Nalpha-dimethyl-, and 4,Nalpha,Nalpha-trimethylhistamines. Agonist activities are reported for stimulation of histamine H1 (guinea-pig ileum) and
G J, Durant, J C, Emmett, C R, Ganellin, A M, Roe, R A, Slater   +4 more
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