Results 131 to 140 of about 9,716 (184)

Histamine H2 receptors and cyclic AMP in brain

Life Sciences, 1974
Abstract The intravenous injection of histamine to 2–3 day old chicks resulted in a rapid and marked increase in the cyclic AMP content of the cerebral hemispheres that had been removed and frozen within 0.5s using a freeze-blowing technique. This response was not antagonized by pretreatment of the chicks with the histamine H1-receptor antagonists ...
S R, Nahorski, K J, Rogers, B M, Smith
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H1and H2 histamine receptors on Aplysia neurones

Nature, 1975
WE have found two types of histamine receptor on neurones of the mollusc Aplysia corresponding to those already known in mammals. The presence of these specific receptors is consistent with the suggestion that histamine acts as a neurotransmitter.
D O, Carpenter, G L, Gaubatz
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Histamine H1 and H2-Receptors at a Ganglionic Synapse

Nature, 1973
MANY humoral agents are capable of modulating synaptic transmission in sympathetic ganglia and it has been proposed that a variety of receptors are present at the ganglionic synapse (see Haefely1). There are thus many possible modulatory mechanisms at this synapse, some of which have a dual nature, the same substance being able both to facilitate and ...
M J, Brimble, D I, Wallis
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Histamine H2-Receptors and Gastric Secretion

1978
In 1966 Ash and Schild1 pointed out for the first time the existence of different types of histamine receptors. They defined as H1 receptors those which could be blocked by the classical antihistaminics and non-H1 receptors those which could not be blocked.
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Antagonism of tolazoline by histamine H2-receptor blockers

Nature, 1975
TOLAZOLINE (2-benzyl-2-imidazoline), a peripheral vasodilator and adrenergic blocking agent used to treat peripheral vascular disease and (formerly) hypertension, has actions similar to those of histamine, including vasodilation, pressor responses in the rabbit and stimulation of intestinal smooth muscle, gastric secretion and the heart.
T O, Yellin, J W, Sperow, S H, Buck
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Prolactin responses to histamine H2 receptor antagonists

Acta Endocrinologica, 1980
Abstract. We have compared the effects of cimetidine and SK&F 92994, a new more potent histamine H2 receptor antagonist, on serum prolactin, and also assessed the effect of the H2 receptor agonist impromidine on the response to cimetidine. As previously reported, cimetidine 200 mg given as an iv bolus dose produced a marked rise in serum prolactin,
P C, Sharpe, M A, Melvin, J G, Mills, W L, Burland, G V, Groom   +4 more
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Stimulation of cerebral histamine H2 receptors by clonidine

Nature, 1976
CLONIDINE (2-[(2,6-dichlorophenyl)amino]-2-imidazoline) is a potent antihypertensive agent whose site of action is believed to be in the central nervous system1 but its mechanism of action is far from clear. Because of its effects on peripheral tissue, it has been generally accepted that the drug stimulates alpha-adrenergic receptors1.
Y, Audigier, A, Virion, J, Schwartz
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[The H1 and H2 histamine receptors].

Allergie et immunologie, 1989
Histamine is a major mediator of the allergic reactions. Histamine have different actions: contraction of smooth muscles, vascular action, increase in gastric and adrenal medulla secretion. Effects on central or peripheral nervous system are discussed. The specific H1 or H2 activity explains the different configurations of histamine. The specificity of
F, Ruff, M C, Santais
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Histamine H2 receptor: Involvement in gastric ulceration

Life Sciences, 1976
The involvement of the H1 and H2 receptors for histamine in the pathogenesis of gastric ulcers was investigated in rats. Metiamide, an H2 receptor antagonist, reliably reduced ulceration produced by stress alone or by a combination of stress and aspirin.
P A, Brown, T H, Brown, J, Vernikos-Danellis   +2 more
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Histamine H2-receptor antagonists.

Advances in internal medicine, 1978
Development of histamine H2-receptor antagonists has enhanced the understanding of histamine physiology and pharmacology. The effect of H2-receptor antagonists on gastrointestinal physiology has been studied extensively. These compounds inhibit gastric acid secretion in response to all known secretagogues and, in contrast to anticholinergic drugs ...
M, Feldman, C T, Richardson
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