Results 181 to 190 of about 784,733 (223)
Some of the next articles are maybe not open access.
Structural elements of H1- and H2-receptors of histamine
General Pharmacology: The Vascular System, 1980Abstract This article sets out the proposed schemes of histamine H 1 - and H 2 -receptors. These schemes are based on the analysis of histamine agonists activity.
L L, Grechishkin +3 more
openaire +2 more sources
Histamine H2 Receptor Biased Signaling Methods
2017Fil: Fernandez, Natalia Cristina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Investigaciones Farmacologicas. Universidad de Buenos Aires. Facultad de Farmacia y Bioquimica.
Fernandez, Natalia Cristina +3 more
openaire +2 more sources
Histamine H2 receptors in rat renal glomeruli
Biochemical Pharmacology, 1982The aim of this study was to demonstrate histamine-H2 receptors in glomeruli isolated from rat renal cortex and to correlate binding to stimulation by histamine of glomerular cyclic AMP concentration. Binding studies were performed at 10-12 degrees C using [3H]cimetidine as a tracer.
D, Chansel +3 more
openaire +2 more sources
Histamine H2-receptors on single central neurones
Nature, 1975THE detection of histamine H2-receptor antagonists1,2 has provided fresh impetus to the investigation of central effects of histamine3–7 and its possible role as a neurotransmitter3,8–10. In the hypothalamus of rat and cat microelectrophoretically applied histamine excites a large number of cells.
H L, Haas, U M, Bucher
openaire +2 more sources
Histamin-H2-Receptor-Antagonismus
1978Receptoren sind als hypothetische Orte an der Zelloberflache aufzufassen, deren Verbindung mit einem Agonisten (physiologischer Wirkstoff oder Pharmakon) von einer spezifischen Leistung der Zelle gefolgt ist. Antagonisten besitzen ebenfalls eine Affinitat zum Receptor, konnen aber die spezifische Wirkung in der Zelle nicht hervorrufen. Sie konkurrieren
openaire +1 more source
Analysis of the histamine H2-receptor in human monocytes
Biochemical Pharmacology, 2014Histamine receptors are G-protein-coupled receptors (GPCRs). Canonically, the histamine H2-receptor (H2R) couples to Gs-proteins and activates adenylyl cyclases (ACs) with subsequent adenosine-3',5'-cyclic monophosphate (cAMP) generation. Recently, the classic two-state model describing GPCR activation has been extended to a multiple-state model ...
Kristin, Werner +2 more
openaire +2 more sources
Histamine H1- and H2-receptors in the gastrointestinal circulation
Naunyn-Schmiedeberg's Archives of Pharmacology, 1980Evidence for the presence of specific histamine H1- and H2-receptors in the gastrointestinal circulation was obtained using histamine, 2-methylhistamine (a specific H1-agonist), 4-methylhistamine (a specific H2-agonist), and selective H1- and H2-receptor antagonists in the anesthetized dog.
G A, Charbon, H A, Brouwers, A, Sala
openaire +2 more sources
Multiple Signaling Pathways of Histamine H2 Receptors
1991Histamine H2 receptor (H2R) has been shown to be coupled to adenylate cyclase. However, we have previously demonstrated that H2R-specific stimulation also activated phospholipase C in human HL-60 promyelocytic leukemia cells (Mitsuhashi M. et al. J. Biol. Chem. 264:18356, 1989).
M, Mitsuhashi, D G, Payan
openaire +2 more sources
1980
Publisher Summary The overall effect of histamine on the airway smooth muscle is highly complex and depends on the algebraic sum of stimulatory and inhibitory actions of a mixed population of H 1 - and H 2 -receptors, which in general act in opposite directions.
openaire +2 more sources
Publisher Summary The overall effect of histamine on the airway smooth muscle is highly complex and depends on the algebraic sum of stimulatory and inhibitory actions of a mixed population of H 1 - and H 2 -receptors, which in general act in opposite directions.
openaire +2 more sources
2015
This review is about clinical pharmacology of histamine H2-receptor antagonists and their prophylactic and therapeutic effects in peptic ulser disease, Zollinger-Ellison Syndrome, gastroesophageal reflux and acute stress ulcers and erosions which are known asid-peptic disorders. H2-receptor blocker drugs (Cimetidine, Ranitidine, Famotidine, Nizatidine)
ACET, Dr. Ahmet, ÖLMEZ, Dr. Ercüment
openaire +1 more source
This review is about clinical pharmacology of histamine H2-receptor antagonists and their prophylactic and therapeutic effects in peptic ulser disease, Zollinger-Ellison Syndrome, gastroesophageal reflux and acute stress ulcers and erosions which are known asid-peptic disorders. H2-receptor blocker drugs (Cimetidine, Ranitidine, Famotidine, Nizatidine)
ACET, Dr. Ahmet, ÖLMEZ, Dr. Ercüment
openaire +1 more source