Results 61 to 70 of about 42,332 (197)

Glucagon‐like peptide‐1 receptor agonist and respiratory complications after endoscopy: A Japanese nationwide cohort study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 316-323, January 2026.
Abstract Aims While discontinuation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) before esophagogastroduodenoscopy (EGD) is not universally mandated, safety concerns persist. Evidence remains insufficient for managing specific patient subgroups, particularly in Asian populations. We aimed to provide evidence for stratified risk assessment in
Hiroyuki Hisada   +13 more
wiley   +1 more source

Allergic manifestations and cutaneous histamine responses in patients with McCune Albright syndrome

open access: yesWorld Allergy Organization Journal, 2013
Background McCune Albright syndrome (MAS) is a rare disorder characterized by precocious puberty, café-au-lait spots, and fibrous dysplasia. Its cause is an activating mutation in the GNAS gene, encoding a subunit of the stimulatory G protein, Gsalpha ...
Jill D Jacobson   +2 more
doaj   +1 more source

Histamine Regulates the Inflammatory Profile of SOD1-G93A Microglia and the Histaminergic System Is Dysregulated in Amyotrophic Lateral Sclerosis

open access: yesFrontiers in Immunology, 2017
Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disease where activated glia release pro-inflammatory cytokines that trigger a vicious cycle of neurodegeneration in the absence of resolution of inflammation.
Savina Apolloni   +11 more
doaj   +1 more source

The Effects of Histaminergic Agents in the Nucleus Accumbens of Rats in the Elevated Plus-Maze Test of Anxiety

open access: yesBasic and Clinical Neuroscience, 2010
Introduction/Aims: The nucleus accumbens (NAc) receives histaminergic neurons from tuberomammillary nuclei. There are also reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Mohammad-Reza Zarrindast   +2 more
doaj   +2 more sources

The effect of common medications on the efficacy of immune checkpoint inhibitors

open access: yesCancer, Volume 131, Issue 24, 15 December 2025.
Abstract Background Medications such as proton pump inhibitors (PPIs), antihistamines, and nonsteroidal anti‐inflammatory drugs have been linked to immune checkpoint inhibitor (ICI) efficacy in patients with non–small cell lung cancer (NSCLC), but these associations may reflect unmeasured confounding rather than true pharmacologic effects.
Daria Brinzevich   +10 more
wiley   +1 more source

Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors

open access: yesJournal of Experimental Medicine, 1991
Histamine and tumor necrosis factor alpha (TNF-alpha) can each contribute to the pathogenesis of allergic reactions and chronic inflammatory diseases.
E. Vannier   +2 more
semanticscholar   +1 more source

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi   +18 more
wiley   +1 more source

Histamine and its Effects Mediated via H3 Receptor – Potential Clinical Applications of H3 Antagonists

open access: yesActa Medica Martiniana, 2013
Histamine is one of the most important biogenic amines and it mediates numbers of physiological processes. It is also involved in majority of inflammatory diseases via its receptors H1, H2, H3 and H4.
Hanuskova E., Plevkova J.
doaj   +1 more source

The Effects of Histaminergic Agents in the Nucleus ccumbens of Rats in the Elevated Plus-Maze Test of Anxiety [PDF]

open access: yesIranian Journal of Psychiatry, 2010
"n Objective: "n The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Ameneh Rezayof   +2 more
doaj  

H3 antagonists and postoperative cognitive dysfunction

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2019
Since histamine (HA) was first synthesized in 1907 and isolated as a bacterial contaminant of an extract of ergot in 1910, its role in health and disease and its molecular mechanism of action have been unraveled, leading to the formulation of an array of
Chandrasekhar Krishnamurti
doaj   +1 more source

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