Results 231 to 240 of about 637,770 (292)

Decoding IgE Fc receptors

Immunologic Research, 2007
Immunoglobulin E (IgE) plays a central role in the pathogenesis of allergic diseases by interacting with two membrane receptors: high-affinity FcepsilonRI and low-affinity FcepsilonRII (CD23). Allergeninduced IgE-occupied FcepsilonRI aggregation on the mast cell or basophil cell surface leads to the activation of intracellular signaling events and ...
Ming, Zhang, Richard F, Murphy, Devendra K, Agrawal   +2 more
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The IgE Receptor

1981
The concept of receptors is derived from the analysis of biologically active substances. Its historical roots can be traced to pioneer pharmacologists such as J.N. Langley who worked with curare, to H.H. Dale who studied ergot alcaloids, and to Paul Ehrlich who investigated chemotherapeutic agents in the early 1900 s.
W. König, K. Theobald, G. Möller, P. Pfeiffer, A. Bohn   +4 more
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Proteolytic fragments of the receptors for IgE

Immunology Letters, 1982
Partially purified IgE receptor(s) of rat basophilic leukemia cells (RBL) designated R and H and having apparent molecular weight of 45,000 and 55,000 daltons, respectively, were subjected to proteolysis with papain. Polyacrylamide gel electrophoresis of the digests in the presence of sodium dodecyl sulfate revealed a difference in the size and number ...
P A, Roth, A, Froese
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The receptor for IgE on blood platelets

European Journal of Immunology, 1986
AbstractHighly purified blood platelets from man and rat could be induced into cytotoxic effectors against schistosome larvae by an IgE‐dependent mechanism. Such a process implied the existence of a receptor for the Fc part of IgE on the surface of these blood elements.
M, Joseph, A, Capron, J C, Ameisen, M, Capron, H, Vorng, V, Pancré, J P, Kusnierz, C, Auriault   +7 more
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The high-affinity receptor for IgE

Current Opinion in Immunology, 1990
Many cells of the immune system have cell-surface receptors that bind IgE with low afhmity [FCE receptor (FcER) II] (Delespesse et al, this issue, pp 506512). In contrast, the high-aifmity receptor for IgE (FcsRI) is found exclusively on the surface of mast cells and basophils.
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Cytofluorometric quantification of IgE and IgE receptors on individual mast cells

Journal of Immunological Methods, 1994
Information about the IgE receptor and IgE content of mast cells under different conditions in vivo is essential for further understanding the functions of the mast cell-IgE system. A cytofluorometric method for measuring cell-bound IgE on individual mast cells was therefore explored using peritoneal mast cells of Sprague-Dawley rats infected with the ...
X J, Chen, S, Juliusson, F, Aldenborg, L, Enerbäck   +3 more
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The IgE Antigen Receptor: A Key Regulator for the Production of IgE Antibodies

International Archives of Allergy and Immunology, 2001
Immunoglobulins in general form a substantial component of serum proteins, and play a role in homeostatic mechanisms, a first line of defense against pathogenic organisms and in immunological memory. In the secreted form, immunoglobulins represent the effector arm of the humoral immune system.
G, Achatz, E, Luger, R, Geisberger, G, Achatz-Straussberger, M, Breitenbach, M, Lamers   +5 more
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The IgE Receptors (Introduction)

1987
It is well-known that stimulation of the receptor, with high affinity for IgE on mast cells and basophils, initiates an allergic reaction. This has been extensively studied during the past 20 years. There is no doubt that this receptor is of major importance in the understanding of allergic diseases.
A. Kulczycki, A. Capron, J.-P. Dessaint, A. B. Tonnel   +3 more
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Induction of Ige Receptors on Human Lymphocytes

Immunological Communications, 1983
A mouse myeloma IgE protein was cross-linked with dimethylsuberimidate to induce polymerization and incubated with normal human peripheral blood T lymphocytes in tissue culture. After 24 hours at 37 degrees C approximately 30% of the cells formed rosettes with IgE sensitized red cells as compared with much lower levels in the controls.
C W, Parker, T, Schechtel, S, Falkenhein, M, Huber   +3 more
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IgE Receptors on Lymphocytes and IgE-Binding Factors

1991
There are two types of Fc receptors for IgE (Fc∈R): the high-affinity Fc∈R (Fc∈RI) (reviewed in Metzger, 1988) and the low-affinity Fc∈R (Fc∈RII) (reviewed in Spiegelberg, 1984). The former is expressed on basophils and mast cells, whereas the latter is expressed on lymphocytes (Lawrence et al., 1975), monocytes and macrophages (A. Capron et al., 1975;
Kwang-Myong Kim, Mitsufumi Mayumi, Haruki Mikawa   +2 more
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