Results 291 to 300 of about 3,330,792 (348)
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International Reviews of Immunology, 1989
Human lymphocytes bear at least three different classes of Fc gamma R, which are different in cellular distribution, structure, and function. This review deals with recent advances in understanding the complexity of huFc gamma R. In particular, studies demonstrating the presence of alternate phosphatidyl inositol glycan-anchored and transmembrane ...
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Human lymphocytes bear at least three different classes of Fc gamma R, which are different in cellular distribution, structure, and function. This review deals with recent advances in understanding the complexity of huFc gamma R. In particular, studies demonstrating the presence of alternate phosphatidyl inositol glycan-anchored and transmembrane ...
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Inflammation in autoimmunity: receptors for IgG revisited
Trends in Immunology, 2001During the past decade, our knowledge of Fc receptor interactions in inflammation has increased dramatically owing to the availability of single and multiple Fc-receptor-deficient mice. The deletion of activating Fc gamma receptors protects against inflammation in models of immune-complex-mediated diseases, whereas the deletion of inhibitory Fc gamma ...
H M, Dijstelbloem +2 more
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IgG‐Fc‐Receptors of Group C Streptococci
Journal of Veterinary Medicine, Series B, 1987SummaryNon‐immune binding of human IgG to streptococci of serological group C could be readily detected on nitrocellulose membranes by direct cultivation of the streptococci or microfiltration of their culture supernatants. Further, quantitative determinations of Fc‐receptor activities with 125I‐IgG preparations revealed, that all 11 cultures of S ...
C, Frede, C, Lämmler, H, Blobel
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IgG receptor polymorphisms: risk factors for disease
Immunogenetics, 1998Two groups of receptors for immunoglobulin G (FcgammaR) can be distinguished. Endothelial cells and placental syncytiotrophoblasts express an MHC class I-like FcgammaR important for regulation of IgG half-life and IgG transport, respectively. FcgammaR expressed on leukocytes constitute a heterogeneous family of membrane bound and soluble proteins.
W, van der Pol, J G, van de Winkel
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IgG receptors on foetal chick yolk sac
Journal of Cell Science, 1978ABSTRACT In the chicken, maternal IgG is deposited in the oocyte yolk and subsequently transported intact by the foetal chick yolk sac into the chick circulation. Such transport appears to require a specific membrane-localized IgG receptor.
C D, Linden, T F, Roth
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IgG Fc Receptors: Evolutionary Considerations
2019Immunoglobulins (Ig), a critical component of the adaptive immune system, are present in all jawed vertebrates and through sophisticated diversification mechanisms are able to recognize antigens of almost infinite diversity. During mammalian evolution, IgG has emerged as the predominant Ig isotype that is elicited upon antigenic challenge, representing
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IgG Receptors in Alzheimer’s Disease
Science Signaling, 2013An interaction between the IgG receptor FcγRIIb and β-amyloid contributes to the neuropathology of Alzheimer’s disease.
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Phagocyte Fc receptors for IgG
1998This chapter focuses on the Fc receptors for IgG (FcγR) on phagocytic cells, e.g. polymorphonuclear neutrophils (PMNs), monocytes and macrophages. Eosinophils and basophils/mast cells which also have phagocytic properties are not discussed. PMNs and monocytes circulate in the bloodstream and are derived from pluripotent haematopoietic stem cells in the
S. E. Mckenzie +2 more
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Characterization of human IgG Fc receptors.
The Journal of Immunology, 1985Abstract A murine monoclonal antibody, KuFc79, has been developed that reacts with human IgG Fc receptors on monocytes, B lymphocytes, and granulocytes. The specificity of KuFc79 for Fc receptors was demonstrated by the ability of Fab fragments to block Fc-mediated phagocytosis by monocytes.
M, Vaughn, M, Taylor, T, Mohanakumar
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Human Lymphocytes with Receptors for IgG
International Archives of Allergy and Immunology, 1974Human lymphocytes with receptors for IgG (EA-RFC) were detected in peripheral blood by their ability to form rosettes with human erythrocytes sensitized with human (Ripley anti-CD) or rabbit IgG. EA-RFC were shown to be different from T-lymphocytes forming rosettes with sheep erythrocytes (E-RFC), both by direct studies of mixed rosette suspensions and
S.S. Frøland +2 more
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