Results 11 to 20 of about 115,500 (292)

Late-onset myasthenia gravis: Is it a different clinical entity?

Neurological Sciences and Neurophysiology, 2021
Objective: The increase in the average life expectancy of humans has resulted in an increased occurrence of late-onset myasthenia gravis (LOMG). It is noticeable that the clinical, immunologic, and prognostic features of patients with LOMG are different ...
Hulya Tireli, Gulbun Yuksel, Kemal Tutkavul   +2 more
doaj   +1 more source

Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19

Biomolecules, 2021
The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell ...
Philippe Youkharibache
doaj   +1 more source

The Dynamic Expression of Potential Mediators of Severe Acute Respiratory Syndrome Coronavirus 2 Cellular Entry in Fetal, Neonatal, and Adult Rhesus Monkeys

Frontiers in Genetics, 2021
The coronavirus disease 2019 (COVID-19) pandemic, induced by the pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly all over the world. There is considerable variability among neonates, children, and adults in the
Bangrong Cao, Liping Zhang, Huifen Liu, Shiqi Ma, Kun Mi   +4 more
doaj   +1 more source

Immunopathogenesis of rheumatoid arthritis [PDF]

, 2017
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
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What Is the Correlation between Preeclampsia and Cancer? The Important Role of Tachykinins and Transition Metal Ions

Pharmaceuticals, 2023
Metal ions are irreplaceable in many biological processes. They are components of numerous metalloproteins and serve as cofactors or structural elements for enzymes.
Klaudia Szczerba, Kamila Stokowa-Soltys
doaj   +1 more source

High-throughput Sequencing Based Immune Repertoire Study during Infectious Disease

Frontiers in Immunology, 2016
The selectivity of the adaptive immune response is based on the enormous diversity of T and B cell antigen-specific receptors. The immune repertoire, the collection of T and B cells with functional diversity in the circulatory system at any given time ...
Dongni Hou, Cuicui Chen, Eric John Seeley, Shujing Chen, Yuanlin Song   +4 more
doaj   +1 more source

Effects of Parathyroid Hormone on Immune Function

Clinical and Developmental Immunology, 2010
Parathyroid hormone (PTH) function as immunologic mediator has become interesting with the recent usage of PTH analogue (teriparatide) in the management of osteoporosis.
Abdallah Sassine Geara, Mario R. Castellanos, Claude Bassil, Georgia Schuller-Levis, Eunkue Park, Marianne Smith, Michael Goldman, Suzanne Elsayegh   +7 more
doaj   +1 more source

Structural Immunology of Complement Receptors 3 and 4 [PDF]

Frontiers in Immunology, 2018
Complement receptors (CR) 3 and 4 belong to the family of beta-2 (CD18) integrins. CR3 and CR4 are often co-expressed in the myeloid subsets of leukocytes, but they are also found in NK cells and activated T and B lymphocytes. The heterodimeric ectodomain undergoes considerable conformational change in order to switch the receptor from a structurally ...
Thomas Vorup-Jensen, Thomas Vorup-Jensen, Rasmus Kjeldsen Jensen   +2 more
openaire   +5 more sources

The Effector Function of Allergens

Frontiers in Allergy, 2022
Allergens are antigens that generate an IgE response (sensitization) in susceptible individuals. The allergenicity of an allergen can be thought of in terms of its ability to sensitize as well as its ability to cross-link IgE/IgE receptor complexes on ...
Stéphane Hazebrouck, Nicole Canon, Stephen C. Dreskin   +2 more
doaj   +1 more source

Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]

, 2005
Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M., Holtje, H. D., Kleuser, B., Korting, Hans Christian, Schäfer-Korting, Monika   +4 more
core   +1 more source