HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Frontiers in Immunology, 2021 Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior.
Baimei Zhuang +4 more
doaj +1 more source
Cortisol patterns are associated with T cell activation in HIV. [PDF]
, 2012 ObjectiveThe level of T cell activation in untreated HIV disease is strongly and independently associated with risk of immunologic and clinical progression. The factors that influence the level of activation, however, are not fully defined.
Acree, Michael +10 more
core +3 more sources
Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective [PDF]
Frontiers in Immunology, 2021 Extracellular nucleotides are important mediators of activation, triggering various responses through plasma membrane P2 and P1 receptors. P2 receptors are further subdivided into ionotropic P2X receptors and G protein-coupled P2Y receptors. P2X4 is an ATP-gated cation channel broadly expressed in most tissues of the body.
Kanellopoulos, Jean M +3 more
openaire +6 more sources
New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. [PDF]
, 2015 Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a
Cameron, Robert B +2 more
core +2 more sources
Flow Cytometric Analysis of Calcium Influx Assay in T cells
Bio-Protocol, 2013 Calcium influx is one of the key signaling events upon stimulation of T cell receptors (TCR) and plays an important role for T cell activation, proliferation, and differentiation.
Sun-Hwa Lee
doaj +1 more source
Viruses, 2022 Herpes simplex virus type 1 (HSV-1), an α subgroup member of the human herpesvirus family, infects cells via the binding of its various envelope glycoproteins to cellular membrane receptors, one of which is herpes virus entry mediator (HVEM), expressed ...
Yang Gao +25 more
doaj +1 more source
A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"? [PDF]
, 2016 With the advent and stunning success of combination antiretroviral therapy (ART) to prolong and improve quality of life for persons with HIV infection, HIV research has been afforded the opportunity to pivot towards studies aimed at finding "a cure." The
Cannon, Paula M +14 more
core +2 more sources
Immunity to pathogens taught by specialized human dendritic cell subsets.
Frontiers in Immunology, 2015 Dendritic cells (DC) are specialized antigen-presenting cells (APC) that have a key role in immune responses, because they bridge the innate and adaptive arms of the immune system.
Jens A. E. Geginat +7 more
doaj +1 more source
Diagnostic Value Parameters Of Acute Phase Reactances Of Infectious-inflammatory Process In Diagnostics Of Early Neonatal Sepsis [PDF]
, 2018 An advanced progress of clinical neonatology in recent years has enabled to achieve considerable success in newborn management with due respect to both medical treatment and general care, especially in the group of neonates with low body weight at birth.
Bezrukov, L. (Leonid) +2 more
core +2 more sources
Application of built-in adjuvants for epitope-based vaccines [PDF]
PeerJ, 2019 Several studies have shown that epitope vaccines exhibit substantial advantages over conventional vaccines. However, epitope vaccines are associated with limited immunity, which can be overcome by conjugating antigenic epitopes with built-in adjuvants (e.
Yao Lei +6 more
doaj +2 more sources