Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]
Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M.+4 more
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Microchimerism, dendritic cell progenitors and transplantation tolerance [PDF]
The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host.
Demetris, AJ+5 more
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Anaesthetic Management of Myasthenia Gravis with Thymic Mass in Facial Trauma [PDF]
Myasthenia gravis is an immunologic disorder characterised by polyclonal antibodies directed against nicotinic acetylcholine receptors at postneuromuscular junction.
Deepak Sharma, Dheer Singh
doaj
HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior.
Baimei Zhuang+4 more
doaj +1 more source
Envelope-receptor interactions in Nipah virus pathobiology. [PDF]
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
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The gut microbiota is essential for the development and regulation of the immune system and the metabolism of the host. Germ-free animals have altered immunity with increased susceptibility to immunologic diseases and show metabolic alterations. Here, we
Martina Spiljar+5 more
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Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy Pathogenesis
Reduced early microbial exposure in early life has become a leading candidate to explain the escalating rate of allergic disease and has generated intense interest in the interaction between the developing immune system and the microbial environment ...
Susan L. Prescott, MD, PhD, FRACP
doaj +1 more source
Toll‐like receptors in pathogenesis of neurodegenerative diseases and their therapeutic potential
Toll‐like receptors (TLRs) are a family of pattern‐recognition receptors triggered by pathogen‐derived and tissue‐damage‐related ligands. TLRs were previously believed to only be expressed in immune cells.
Yosef Tsegaye Dabi+2 more
doaj +1 more source
Treatment of Adult Patients with Relapsed/Refractory B-Cell Philadelphia-Negative Acute Lymphoblastic Leukemia [PDF]
The majority of adult patients affected by B-cell acute lymphoblastic leukemia (B-ALL) will relapse after an initial response, while approximately 20% will display primary resistant disease. Patients suffering from relapsed/refractory B-ALL have a very
Lanza, Francesco+2 more
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Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective [PDF]
Extracellular nucleotides are important mediators of activation, triggering various responses through plasma membrane P2 and P1 receptors. P2 receptors are further subdivided into ionotropic P2X receptors and G protein-coupled P2Y receptors. P2X4 is an ATP-gated cation channel broadly expressed in most tissues of the body.
Kanellopoulos, Jean M+3 more
openaire +6 more sources