Results 81 to 90 of about 1,450,855 (188)

Targeting neutrophil-driven inflammation in adult-onset still’s disease: molecular insights from gene expression profiles

Arthritis Research & Therapy
Background The rarity and heterogeneity of adult-onset Still’s disease (AOSD) pose significant challenges in understanding its precise pathogenic mechanisms, developing effective treatment options, and establishing therapeutic strategies. A comprehensive
In-Woon Baek, Hyoun-Ah Kim, Kyung-Su Park, Ki-Jo Kim   +3 more
doaj   +1 more source

Macrophage-derived factors increase low density lipoprotein uptake and receptor number in cultured human liver cells.

Journal of Lipid Research, 1991
Recent evidence suggests the possibility that macrophages can influence lipoprotein metabolism. Therefore we investigated the ability of cultured macrophages to alter low density lipoprotein (LDL) uptake in a human liver cell line (HepG2).
RI Grove, C Mazzucco, N Allegretto, PA Kiener, G Spitalny, SF Radka, M Shoyab, M Antonaccio, GA Warr   +8 more
doaj   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage

Viruses, 2019
Multisystemic inflammation in pigs affected by porcine circovirus type 2 (PCV2) indicates the disordered expression of inflammatory cytokines. However, the PCV2-induced expression profile of inflammation cytokines and its regulating mechanism remain ...
Shunli Yang, Baohong Liu, Shuanghui Yin, Youjun Shang, Xinming Zhang, Muhammad Umar Zafar Khan, Xiangtao Liu, Jianping Cai   +7 more
doaj   +1 more source

IL-38: A New Player in Inflammatory Autoimmune Disorders

Biomolecules, 2019
Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36
Lihui Xie, Zhaohao Huang, He Li, Xiuxing Liu, Song Guo Zheng, Wenru Su   +5 more
doaj   +1 more source

Molecular Mechanism of NLRP3 Inflammasome in Inflammatory Diseases and Tumors

Immunity, Inflammation and Disease
The nucleotide‐binding and oligomerization domain‐like receptors (NLRs) are pattern recognition receptors. Nucleotide‐binding oligomerization domain‐like receptor family pyrin domain‐containing 3 (NLRP3), a member of the NLRs family, can form a protein ...
Le‐Lan Gong, He‐Jiang Zhou, Quan‐Ming Zhao, Ning Xu, Feng‐Chang Huang, Ling‐Yan Su, Wen‐Liang Li   +6 more
doaj   +1 more source

Inflammasome in Intestinal Inflammation and Cancer

Mediators of Inflammation, 2013
The activation of specific cytosolic pathogen recognition receptors, the nucleotide-binding-oligomerization-domain- (NOD-) like receptors (NLRs), leads to the assembly of the inflammasome, a multimeric complex platform that activates caspase-1.
Tiago Nunes, Heitor S. de Souza
doaj   +1 more source

Interactions Between Candida albicans and Host
Interações entre Candida albicans e Hospedeiro

Semina: Ciências Biológicas e da Saúde, 2011
Candida albicans can cause grave infections in patients who are immunocompromised by diseases, by surgery, or by immunesupresive therapy. The high levels of morbidity and mortality resulting from those infections in hospitalized patients show that C ...
Tatiane De Rossi, Marcell Alysson Batisti Lozovoy, Rosiane Valeriano da Silva, Eduardo Vignoto Fernandes, Thais Herrero Geraldino, Ivete Conchon Costa, Halha Ostrenski Saridakis, Maria Angelica Ehara Watanabe, Ionice Felipe   +8 more
doaj  

Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]

, 2002
Kaiser, Pete, Kogut, Michael, Rothwell, Lisa   +2 more
core   +1 more source

Ligands and Receptors of the Interleukin-1 family in immunity and disease

Frontiers in Immunology, 2013
Cecilia eGarlanda, Alberto eMantovani, Alberto eMantovani   +2 more
doaj   +1 more source