Results 221 to 230 of about 4,744,260 (250)

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Targeting NR4A1 (Nur77) in Macrophage Polarization: Molecular Mechanisms and Translational Prospects for Cardiac Repair After Myocardial Infarction. [PDF]

Int J Mol Sci
Lin J, Wang J, Sun L, Zhang R.
europepmc   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

The multisystem impact of perimenopausal hormonal fluctuations on chronic disease risk. [PDF]

Front Endocrinol (Lausanne)
Luo L, Li L, Wang X, Bai W.
europepmc   +1 more source

Immunoregulatory mechanisms in parasitic eosinophilic lung disease: the role of IgE immune complexes and NLRC4 inflammasome. [PDF]

Front Immunol
Cao Y, Rao D, Peng Z, Chen Z, Xia Q, Xie C, Fu Y, Huang D, Zhang Z, Yao C.   +9 more
europepmc   +1 more source

Microbiota-innate immune crosstalk drives atherosclerosis: mechanisms, disease progression, and emerging therapeutic strategies. [PDF]

Front Immunol
Li Y, Zhu J, Huang M, Liu X, Wang L.
europepmc   +1 more source

The language of the immune system: Part 1: Cytokine conversations and conversationalists. [PDF]

Immunohorizons
Rosenthal KS.
europepmc   +1 more source

Neuroimmune interactions: from molecular mechanisms to therapeutic targets. [PDF]

Mol Biomed
Hao YH, Shi RJ, Tang YL, Liang XH.
europepmc   +1 more source