Results 241 to 250 of about 289,750 (311)

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Interleukin-17 receptor-A signalling: atheroprotective role in JAK2 clonal haematopoiesis

European Heart Journal
Kun Zhao, Cheng-Chieh Hsu, Yash Pershad, Caitlyn Vlasschaert, Robert W Corty, Nan Wang, Jonathan Brett Heimlich, Alan R Tall, Alexander G Bick   +8 more
openaire   +2 more sources

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

Advanced Science, EarlyView.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu, Wenjuan Tang, Handan Zhang, Jie Liu, Jiaqi Zhang, Yu Yao, Xiao Fu, Xin Chen, Yanmin Zhang   +8 more
wiley   +1 more source

Can angiotensin II affect the inflammatory response of human dental pulp cells in vitro? [PDF]

J Appl Oral Sci
Colombini-Ishikiriama BL, Dionisio TJ, Garbieri TF, Silva RAD, Oliveira SHP, Lara VS, Greene AS, Santos CFD.   +7 more
europepmc   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Targeting the Epithelial Alarmin Axis with Biomedical Nanoparticles: A New Frontier in Allergic Asthma Therapy. [PDF]

Int J Nanomedicine
Yang Y.
europepmc   +1 more source

Genome-wide transcriptome analysis of dendritic cells in a model of acute and persistent infection [PDF]

, 2013
Filkor Kata
core  

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

A Chemically Defined Four‐Component Self‐Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity

Advanced Science, EarlyView.
A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming, Renyu Zhang, Xiaohui Li, Guiqi Li, Yu Niu, Deying Yang, Xiang Luo, Jun Liao, Zhongqiu Liu, Guochao Liao   +9 more
wiley   +1 more source

Soluble cytokine receptor levels in obstructive sleep apnea patients treated with continuous positive airway pressure therapy. [PDF]

Future Sci OA
Kiriluk SH, Freeburg LA, Khan S, McAlpine CS, Cohen O, Kundel V, Saurez-Farinas M, Spinale FG, Shah N.   +8 more
europepmc   +1 more source