Results 31 to 40 of about 269,474 (266)

Adenine Decreases Hypertrophic Effects through Interleukin-18 Receptor

Chinese Journal of Physiology, 2019
Cardiac hypertrophy is the main cause of heart failure. Levels of circulating interleukin-18 (IL-18) have been reported to increase in congestive heart disease and cardiac hypertrophy. Relationships among IL-18 levels, IL-18 receptor (IL-18R) expression, and cardiac hypertrophy remain unclear.
Yi-Feng Yang, Yao-Jen Liang
openaire   +3 more sources

Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling [PDF]

Journal of Biological Chemistry, 1998
We have identified a novel member of the interleukin-1 (IL-1) receptor family, which we have termed AcPL. In transient transfection assays, we were unable to demonstrate a role for AcPL in IL-1-induced activation of NFkappaB. Interleukin-18 (interferon-gamma-inducing factor) is another member of the IL-1 family of cytokines, and it has recently been ...
T L, Born, E, Thomassen, T A, Bird, J E, Sims   +3 more
openaire   +2 more sources

TRAF Regulation of IL-17 Cytokine Signaling

Frontiers in Immunology, 2019
Tumor necrosis factor receptor (TNFR)-associated factors or (TRAFs) are important mediators of Interleukin-17 (IL-17) cytokine signaling and contribute to driving tissue responses that are crucial for protective immunity but are often implicated in ...
Shadi Swaidani, Shadi Swaidani, Caini Liu, Junjie Zhao, Katarzyna Bulek, Xiaoxia Li   +5 more
doaj   +1 more source

NLRP3-Mediated Inflammation in Atherosclerosis and Associated Therapeutics

Frontiers in Cell and Developmental Biology, 2022
The NLRP3 inflammasome is a crucial constituent of the body’s innate immune system, and a multiprotein platform which is initiated by pattern recognition receptors (PRRs). Its activation leads to caspase-1 maturation and release of inflammatory cytokines,
Na Lu, Weijia Cheng, Dongling Liu, Gang Liu, Can Cui, Can Cui, Chaoli Feng, Xianwei Wang, Xianwei Wang   +8 more
doaj   +1 more source

Inflammatory cytokines, soluble interleukin-6 receptors, and fragmented cytokeratin-18 as indicators of non-alcoholic steatohepatitis

Терапевтический архив
Aim. To evaluate inflammatory cytokines, such as tumor necrosis factor α (TNF-α), interleukin (IL)-1β, 8, 6, soluble IL-6 receptors (sIL-6R) and fragmented cytokeratin-18 (FCK-18) as indicators of non-alcoholic steatohepatitis (NASH).
Anastasia A. Shipovskaya, Olga P. Dudanova, Irina V. Kurbatova   +2 more
doaj   +1 more source

Pathogens and Dead Cells Cooperate with Cytokines in Activating the Innate and Adaptive Response

European Journal of Inflammation, 2011
After microbial invasion and tissue damage, a set of cytokines, including interleukin-1α (IL-1α), IL-1β, IL-6, IL-18 and tumor necrosis factor-α (TNF-α), and microbial and endogenous molecules named pathogen-associated molecular pattern (PAMPs) and ...
J.E. Belizário
doaj   +1 more source

Macrophage-derived factors increase low density lipoprotein uptake and receptor number in cultured human liver cells.

Journal of Lipid Research, 1991
Recent evidence suggests the possibility that macrophages can influence lipoprotein metabolism. Therefore we investigated the ability of cultured macrophages to alter low density lipoprotein (LDL) uptake in a human liver cell line (HepG2).
RI Grove, C Mazzucco, N Allegretto, PA Kiener, G Spitalny, SF Radka, M Shoyab, M Antonaccio, GA Warr   +8 more
doaj   +1 more source

Interleukin-18 Receptor α Modulates the T Cell Response in Food Allergy

Allergy, Asthma & Immunology Research, 2022
The prevalence of food allergy, triggered by T-helper type 2 (Th2) cell-mediated inflammation, is increasing worldwide. Interleukin (IL)-18 plays an important role in inflammatory diseases by binding with the IL-18 receptor. IL-18/IL-18 receptor α (IL-18Rα) is a cofactor for immunoglobulin E (IgE) production and Th2 cell development.
Eun Gyul Kim, Ji Su Leem, Seung Min Baek, Hye Rin Kim, Kyung Won Kim, Mi Na Kim, Myung Hyun Sohn   +6 more
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Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice [PDF]

Scientific Reports, 2015
AbstractBrown and beige adipocytes recruitment in brown (BAT) or white adipose tissue, mainly in the inguinal fat pad (iWAT), meet the need for temperature adaptation in cold-exposure conditions and protect against obesity in face of hypercaloric diets.
Pazos Mendoza, Patricia, Lima Rodríguez, Luis, Tovar Carro, Sulay A., González Touceda, David, Diéguez González, Carlos, García García, María del Carmen   +5 more
openaire   +3 more sources