Results 41 to 50 of about 5,465,732 (298)
The Correlation of CD206, CD209, and Disease Severity in Behçet’s Disease with Arthritis
The purpose of this study was to clarify the role of pattern recognition receptors in Behçet’s disease (BD). The frequencies of several pattern recognition receptors (CD11b, CD11c, CD32, CD206, CD209, and dectin-1) were analyzed in patients with BD by ...
Bunsoon Choi +4 more
doaj +1 more source
Adenine Decreases Hypertrophic Effects through Interleukin-18 Receptor
Cardiac hypertrophy is the main cause of heart failure. Levels of circulating interleukin-18 (IL-18) have been reported to increase in congestive heart disease and cardiac hypertrophy. Relationships among IL-18 levels, IL-18 receptor (IL-18R) expression, and cardiac hypertrophy remain unclear.
Yi-Feng Yang, Yao-Jen Liang
openaire +3 more sources
Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling [PDF]
We have identified a novel member of the interleukin-1 (IL-1) receptor family, which we have termed AcPL. In transient transfection assays, we were unable to demonstrate a role for AcPL in IL-1-induced activation of NFkappaB. Interleukin-18 (interferon-gamma-inducing factor) is another member of the IL-1 family of cytokines, and it has recently been ...
T L, Born +3 more
openaire +2 more sources
TRAF Regulation of IL-17 Cytokine Signaling
Tumor necrosis factor receptor (TNFR)-associated factors or (TRAFs) are important mediators of Interleukin-17 (IL-17) cytokine signaling and contribute to driving tissue responses that are crucial for protective immunity but are often implicated in ...
Shadi Swaidani +5 more
doaj +1 more source
Pathogens and Dead Cells Cooperate with Cytokines in Activating the Innate and Adaptive Response
After microbial invasion and tissue damage, a set of cytokines, including interleukin-1α (IL-1α), IL-1β, IL-6, IL-18 and tumor necrosis factor-α (TNF-α), and microbial and endogenous molecules named pathogen-associated molecular pattern (PAMPs) and ...
J.E. Belizário
doaj +1 more source
NLRP3-Mediated Inflammation in Atherosclerosis and Associated Therapeutics
The NLRP3 inflammasome is a crucial constituent of the body’s innate immune system, and a multiprotein platform which is initiated by pattern recognition receptors (PRRs). Its activation leads to caspase-1 maturation and release of inflammatory cytokines,
Na Lu +8 more
doaj +1 more source
Aim. To evaluate inflammatory cytokines, such as tumor necrosis factor α (TNF-α), interleukin (IL)-1β, 8, 6, soluble IL-6 receptors (sIL-6R) and fragmented cytokeratin-18 (FCK-18) as indicators of non-alcoholic steatohepatitis (NASH).
Anastasia A. Shipovskaya +2 more
doaj +1 more source
Role of interleukin 18 in rheumatoid arthritis [PDF]
No abstract ...
Liew, Foo Y. +4 more
core +1 more source
Recent evidence suggests the possibility that macrophages can influence lipoprotein metabolism. Therefore we investigated the ability of cultured macrophages to alter low density lipoprotein (LDL) uptake in a human liver cell line (HepG2).
RI Grove +8 more
doaj +1 more source
Interleukin-18 Receptor α Modulates the T Cell Response in Food Allergy
The prevalence of food allergy, triggered by T-helper type 2 (Th2) cell-mediated inflammation, is increasing worldwide. Interleukin (IL)-18 plays an important role in inflammatory diseases by binding with the IL-18 receptor. IL-18/IL-18 receptor α (IL-18Rα) is a cofactor for immunoglobulin E (IgE) production and Th2 cell development.
Eun Gyul Kim +6 more
openaire +3 more sources

