Results 31 to 40 of about 61,846,700 (305)

Interleukin 21: a cytokine/cytokine receptor system that has come of age [PDF]

open access: yesJournal of Leukocyte Biology, 2008
AbstractInterleukin-21 (IL-21) and its receptor represent the sixth cytokine system whose actions were recognized to require the common cytokine receptor γ chain. IL-21 is produced by activated CD4+ T cells, natural killer T cells, and follicular T helper cells and has actions on a range of lymphohematopoietic lineages.
Warren J, Leonard   +2 more
openaire   +2 more sources

Expression and Correlation of IgG4 and IL-21 in Collagen-Induced Arthritis Rats

open access: yesJournal of Inflammation Research, 2021
Zhen-Yi Long,1,* Yi-Feng Zhou,2,* Hao Yuan,1 Ya-Meng Peng,1 Si-Xian Wu,1 Fang Peng1 1Department of Clinical Laboratory, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410005, People’s ...
Long ZY   +5 more
doaj  

Association of COVID-19 and Down Syndrome; a Systematic Review

open access: yesBiology and Life Sciences Forum, 2022
Background: COVID-19 has become a global concern. Many risk factors have been identified. Down syndrome, which is 21 trisomy, affects the mental and physical health of the patient.
Dua Ahmed Ali   +2 more
doaj   +1 more source

Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]

open access: yes, 2002
Interleukin-2 (IL-2) exercises an array of biological effects on many cells including the functional activation of cells of the innate immune response.
Pete Kaiser   +5 more
core   +1 more source

Dietary 25-Hydroxyvitamin D3 Supplementation Modulates Intestinal Cytokines in Young Broiler Chickens

open access: yesFrontiers in Veterinary Science, 2022
Vitamin D signaling is important for intestinal homeostasis. An increase in vitamin D receptors in immune cells can modulate cell phenotype and cytokine secretion.
Gerardo A. Abascal-Ponciano   +5 more
doaj   +1 more source

Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer [PDF]

open access: yesCells, 2019
Pancreatic ductal adenocarcinoma (PDAC) displays a marked fibro-inflammatory microenvironment in which infiltrated immune cells fail to eliminate the tumor cells and often—rather paradoxically—promote tumor progression. Of special interest are tumor-promoting T cells that assume a Th17-like phenotype because their presence in PDAC tissue is associated ...
Alica Linnebacher   +11 more
openaire   +3 more sources

GTS-21 has cell-specific anti-inflammatory effects independent of α7 nicotinic acetylcholine receptors.

open access: yesPLoS ONE, 2019
α7 Nicotinic acetylcholine receptors (nAChRs) reportedly reduce inflammation by blocking effects of the important pro-inflammatory transcription factor, nuclear factor kappa-light chain-enhancer of B cells (NFκB).
Brijesh K Garg, Ralph H Loring
doaj   +1 more source

Expression of functional interleukin‐21 receptor on adult T‐cell leukaemia cells [PDF]

open access: yesBritish Journal of Haematology, 2004
SummaryAdult T‐cell leukaemia (ATL) is caused by human T‐cell leukaemia virus type I (HTLV‐I). It has been suggested that cytokines play a role in the development and in the neoplastic cell growth of ATL. However, the precise mechanism involved in this process still remains unclear.
Maki, Ueda   +5 more
openaire   +2 more sources

The Immune Landscape of Hepatitis B Virus-Related Acute Liver Failure by Integration Analysis

open access: yesJournal of Immunology Research, 2022
Hepatitis B virus-related acute liver failure (HBV-ALF) is a common type of liver failure, associated with high short-term mortality and morbidity rates.
Jiao Gong   +9 more
doaj   +1 more source

Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells [PDF]

open access: yes, 2009
Uterine fibroids are benign tumors that arise from the smooth-muscle uterine cells (myometrium) and are the most common uterine disorder occurring in as many as 30% of women over 35 years of age. Despite their frequent occurrence, the etiology of uterine
Abera, Aron Berhanie
core   +1 more source

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