Results 51 to 60 of about 10,025,178 (148)

CLINICAL CASE OF TOCILIZUMAB USE IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

open access: yesПедиатрическая фармакология, 2014
The article presents a case of successful use of a preparation of monoclonal antibodies to interleukin 6 receptors (tocilizumab) at asevere systemic juvenile idiopathic arthritis.
O. L. Lomakina   +4 more
doaj   +1 more source

Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]

open access: yes, 2002
Interleukin-2 (IL-2) exercises an array of biological effects on many cells including the functional activation of cells of the innate immune response.
Pete Kaiser   +5 more
core   +1 more source

Role of Interleukin-6 and Its Receptor in Endometriosis [PDF]

open access: yesMedical Science Monitor, 2017
BACKGROUND Studies have shown that the concentration of interleukin (IL)-6 in peritoneal fluid is increased in patients with endometriosis; however, whether the disorders involving IL-6 contribute to the development of endometriosis is still unclear.
Li, Shihui   +5 more
openaire   +2 more sources

Association of vitamin D deficiency and inflammatory cytokines with the clinicopathological features of breast cancer in female Saudi patients

open access: yesEuropean Journal of Inflammation, 2022
Breast cancer is the leading cause of cancer-related death among women in Saudi Arabia. Many studies have suggested a strong correlation between vitamin D and multiple types of cancer.
Amal F Gharib   +8 more
doaj   +1 more source

Characterization of a gp130 Signaling Receptor Polymorphism [PDF]

open access: yes, 2013
We previously reported an association between human herpesvirus 8 (HHV-8) seroprevalence and increased prostate cancer risk among men on the Caribbean island of Tobago.
Kercher, Katherine
core  

Type of Inflammation Differentially Affects Expression of Interleukin 1β and 6, Tumor Necrosis Factor-α and Toll-Like Receptors in Subclinical Endometritis in Mares. [PDF]

open access: yesPLoS ONE, 2016
Mares that fail to conceive or lose their embryos, without showing typical signs of clinical endometritis, should be suspected of subclinical endometritis (SE).
Marta J Siemieniuch   +5 more
doaj   +1 more source

Roles of tumor necrosis factor-α and interleukin-6 in regulating bone cancer pain via TRPA1 signal pathway and beneficial effects of inhibition of neuro-inflammation and TRPA1

open access: yesMolecular Pain, 2019
Background Pain is one of the most common and distressing symptoms suffered by patients with progression of bone cancer; however, the mechanisms responsible for hyperalgesia are not well understood.
Ding Zhao   +5 more
doaj   +1 more source

CLINICAL CASE OF TOCILIZUMAB THERAPY IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

open access: yesПедиатрическая фармакология, 2013
The article presents a case of successful application of a monoclonal antibodies drug to interleukin 6 receptors (tocilizumab) at severe systemic juvenile idiopathic arthritis with the development of secondary hemophagocytic syndrome.
E. I. Alexeeva   +3 more
doaj   +1 more source

Low-power laser irradiation suppresses inflammatory response of human adipose-derived stem cells by modulating intracellular cyclic AMP level and NF-κB activity. [PDF]

open access: yesPLoS ONE, 2013
Mesenchymal stem cell (MSC)-based tissue regeneration is a promising therapeutic strategy for treating damaged tissues. However, the inflammatory microenvironment that exists at a local injury site might restrict reconstruction.
Jyun-Yi Wu   +5 more
doaj   +1 more source

Investigating plasticity within the interleukin-6 family with AlphaFold-Multimer

open access: yesComputational and Structural Biotechnology Journal
Cytokines are important soluble mediators that are involved in physiological and pathophysiological processes. Among them, members of the interleukin-6 (IL-6) family of cytokines have gained remarkable attention, because especially the name-giving ...
Stefan Düsterhöft   +2 more
doaj   +1 more source

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