Results 31 to 40 of about 309,711 (266)
Autocrine Regulation of UVA-Induced IL-6 Production via Release of ATP and Activation of P2Y Receptors. [PDF]
PLoS ONE, 2015 Extracellular nucleotides, such as ATP, are released from cells in response to various stimuli and act as intercellular signaling molecules through activation of P2 receptors.
Ayumi Kawano +5 more
doaj +1 more source
Pathogens, 2014 Epithelial cells represent the first line of host immune defense at mucosal surfaces. Although opioids appear to increase host susceptibility to infection, no studies have examined opioid effects on epithelial immune functions.
Amanda J. Brosnahan +3 more
doaj +1 more source
Frontiers in GeneticsBackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Jia-wei Ma +3 more
doaj +1 more source
Biomedicines, 2021 Several stimuli can change maternal hormone levels during pregnancy. These changes may affect trophoblastic cells and modulate the development of the embryo and the placental tissue itself.
Talita Guerreiro Rodrigues Húngaro +6 more
doaj +1 more source
Effects of ulinastatin on global ischemia via brain pro-inflammation signal
Translational Neuroscience, 2016 Ulinastatin [urinary trypsin inhibitor (UTI)] plays an important role in the protection of organs against ischemic injury during severe inflammation.
Jiang Xiao-Ming +5 more
doaj +1 more source
Research in Pharmaceutical Sciences, 2021 Background and purpose: Kaempferol (KM), a flavonoid, has an anti-inflammatory and anticancer effect and prevents many metabolic diseases. Nonetheless, very few studies have been done on the antinociceptive effects of KM. This research aimed at assessing
Sajjad Jabbari +4 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The effect of interleukin‐6 and the interleukin‐6 receptor on glucose transport in mouse skeletal muscle [PDF]
Experimental Physiology, 2009 Exercise results in an increase in interleukin‐6 (IL‐6), its receptor (IL‐6R) and skeletal muscle glucose transport. Interleukin‐6 has been found to have equivocal effects on glucose transport, with no studies, to our knowledge, investigating any potential role of IL‐6R.
Gray, S.R. +4 more
openaire +4 more sources